• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Algorithms and software for stochastic simulation of biochemical reacting systems.用于生化反应系统随机模拟的算法与软件。
Biotechnol Prog. 2008 Jan-Feb;24(1):56-61. doi: 10.1021/bp070255h. Epub 2007 Sep 26.
2
Discrete stochastic simulation methods for chemically reacting systems.化学反应系统的离散随机模拟方法。
Methods Enzymol. 2009;454:115-40. doi: 10.1016/S0076-6879(08)03805-6.
3
StochKit2: software for discrete stochastic simulation of biochemical systems with events.StochKit2:用于具有事件的生化系统离散随机模拟的软件。
Bioinformatics. 2011 Sep 1;27(17):2457-8. doi: 10.1093/bioinformatics/btr401. Epub 2011 Jul 4.
4
Discrete-time stochastic modeling and simulation of biochemical networks.生化网络的离散时间随机建模与仿真
Comput Biol Chem. 2008 Aug;32(4):292-7. doi: 10.1016/j.compbiolchem.2008.03.018. Epub 2008 Apr 10.
5
A constrained approach to multiscale stochastic simulation of chemically reacting systems.约束方法在多尺度化学反应系统随机模拟中的应用。
J Chem Phys. 2011 Sep 7;135(9):094102. doi: 10.1063/1.3624333.
6
Automatic identification of model reductions for discrete stochastic simulation.用于离散随机模拟的模型降阶的自动识别。
J Chem Phys. 2012 Jul 21;137(3):034106. doi: 10.1063/1.4733563.
7
Stochastic simulation of chemical kinetics.化学动力学的随机模拟。
Annu Rev Phys Chem. 2007;58:35-55. doi: 10.1146/annurev.physchem.58.032806.104637.
8
Hybrid deterministic/stochastic simulation of complex biochemical systems.复杂生化系统的混合确定性/随机模拟
Mol Biosyst. 2017 Nov 21;13(12):2672-2686. doi: 10.1039/c7mb00426e.
9
Stochastic simulation algorithms for computational systems biology: Exact, approximate, and hybrid methods.计算系统生物学的随机模拟算法:精确、近似和混合方法。
Wiley Interdiscip Rev Syst Biol Med. 2019 Nov;11(6):e1459. doi: 10.1002/wsbm.1459. Epub 2019 Jul 1.
10
Moment estimation for chemically reacting systems by extended Kalman filtering.用扩展卡尔曼滤波对化学反应系统进行矩估计。
J Chem Phys. 2011 Oct 28;135(16):165102. doi: 10.1063/1.3654135.

引用本文的文献

1
A multiscale compartment-based model of stochastic gene regulatory networks using hitting-time analysis.基于击中时间分析的随机基因调控网络多尺度分区模型。
J Chem Phys. 2021 May 14;154(18):184105. doi: 10.1063/5.0010764.
2
BiPSim: a flexible and generic stochastic simulator for polymerization processes.BiPSim:一种用于聚合过程的灵活通用的随机模拟器。
Sci Rep. 2021 Jul 8;11(1):14112. doi: 10.1038/s41598-021-92833-5.
3
Reaction Kinetic Models of Antibiotic Heteroresistance.抗生素异质性耐药反应动力学模型。
Int J Mol Sci. 2019 Aug 15;20(16):3965. doi: 10.3390/ijms20163965.
4
Simulation and inference algorithms for stochastic biochemical reaction networks: from basic concepts to state-of-the-art.随机生化反应网络的模拟与推断算法:从基本概念到最新技术。
J R Soc Interface. 2019 Feb 28;16(151):20180943. doi: 10.1098/rsif.2018.0943.
5
Spatially extended hybrid methods: a review.空间扩展混合方法:综述。
J R Soc Interface. 2018 Feb;15(139). doi: 10.1098/rsif.2017.0931.
6
Inferring Mechanistic Parameters from Amyloid Formation Kinetics by Approximate Bayesian Computation.通过近似贝叶斯计算从淀粉样蛋白形成动力学推断机制参数
Biophys J. 2017 Mar 14;112(5):868-880. doi: 10.1016/j.bpj.2017.01.011.
7
Multiple driving forces required for efficient secretion of autotransporter virulence proteins.自转运毒力蛋白的高效分泌需要多种驱动力。
J Biol Chem. 2015 Apr 17;290(16):10104-16. doi: 10.1074/jbc.M114.629170. Epub 2015 Feb 10.
8
Lazy Updating of hubs can enable more realistic models by speeding up stochastic simulations.中心节点的延迟更新可以通过加速随机模拟来实现更现实的模型。
J Chem Phys. 2014 Nov 28;141(20):204109. doi: 10.1063/1.4901114.
9
Computational strategies for a system-level understanding of metabolism.计算策略用于系统水平理解代谢。
Metabolites. 2014 Nov 24;4(4):1034-87. doi: 10.3390/metabo4041034.
10
Deconstructing stem cell population heterogeneity: single-cell analysis and modeling approaches.解析干细胞群体异质性:单细胞分析和建模方法。
Biotechnol Adv. 2013 Nov 15;31(7):1047-62. doi: 10.1016/j.biotechadv.2013.09.001. Epub 2013 Sep 11.

本文引用的文献

1
Adaptive explicit-implicit tau-leaping method with automatic tau selection.具有自动步长选择的自适应显隐式τ-跳跃方法
J Chem Phys. 2007 Jun 14;126(22):224101. doi: 10.1063/1.2745299.
2
Comment on "nested stochastic simulation algorithm for chemical kinetic systems with disparate rates" [J. Chem. Phys. 123, 194107 (2005)].对《具有不同反应速率的化学动力学系统的嵌套随机模拟算法》的评论 [《化学物理杂志》123, 194107 (2005)]。
J Chem Phys. 2007 Apr 7;126(13):137101; discussion 137102. doi: 10.1063/1.2567036.
3
Spectral methods for parametric sensitivity in stochastic dynamical systems.随机动力系统中参数敏感性的谱方法。
Biophys J. 2007 Jan 15;92(2):379-93. doi: 10.1529/biophysj.106.085084. Epub 2006 Nov 3.
4
Efficient step size selection for the tau-leaping simulation method.用于τ跳跃模拟方法的高效步长选择
J Chem Phys. 2006 Jan 28;124(4):044109. doi: 10.1063/1.2159468.
5
The finite state projection algorithm for the solution of the chemical master equation.用于求解化学主方程的有限状态投影算法。
J Chem Phys. 2006 Jan 28;124(4):044104. doi: 10.1063/1.2145882.
6
An equation-free probabilistic steady-state approximation: dynamic application to the stochastic simulation of biochemical reaction networks.一种无方程概率稳态近似:在生化反应网络随机模拟中的动态应用
J Chem Phys. 2005 Dec 1;123(21):214106. doi: 10.1063/1.2131050.
7
The sorting direct method for stochastic simulation of biochemical systems with varying reaction execution behavior.具有不同反应执行行为的生化系统随机模拟的排序直接方法。
Comput Biol Chem. 2006 Feb;30(1):39-49. doi: 10.1016/j.compbiolchem.2005.10.007.
8
Nested stochastic simulation algorithm for chemical kinetic systems with disparate rates.用于具有不同反应速率的化学动力学系统的嵌套随机模拟算法
J Chem Phys. 2005 Nov 15;123(19):194107. doi: 10.1063/1.2109987.
9
On the origins of approximations for stochastic chemical kinetics.关于随机化学动力学近似方法的起源
J Chem Phys. 2005 Oct 22;123(16):164115. doi: 10.1063/1.2062048.
10
Accelerated stochastic simulation of the stiff enzyme-substrate reaction.刚性酶-底物反应的加速随机模拟
J Chem Phys. 2005 Oct 8;123(14):144917. doi: 10.1063/1.2052596.

用于生化反应系统随机模拟的算法与软件。

Algorithms and software for stochastic simulation of biochemical reacting systems.

作者信息

Li Hong, Cao Yang, Petzold Linda R, Gillespie Daniel T

机构信息

Department of Computer Science, University of California Santa Barbara, Santa Barbara, California 93106, USA.

出版信息

Biotechnol Prog. 2008 Jan-Feb;24(1):56-61. doi: 10.1021/bp070255h. Epub 2007 Sep 26.

DOI:10.1021/bp070255h
PMID:17894470
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2664303/
Abstract

Traditional deterministic approaches for simulation of chemically reacting systems fail to capture the randomness inherent in such systems at scales common in intracellular biochemical processes. In this manuscript, we briefly review the state of the art in discrete stochastic and multiscale algorithms for simulation of biochemical systems and we present the StochKit software toolkit.

摘要

用于模拟化学反应系统的传统确定性方法无法捕捉细胞内生化过程中常见尺度下此类系统所固有的随机性。在本手稿中,我们简要回顾了用于生化系统模拟的离散随机和多尺度算法的当前技术水平,并展示了StochKit软件工具包。