van Norren Dirk, van de Kraats Jan
University Medical Center Utrecht, Department of Ophthalmology AZU E03.136, PO Box 85500, NL-3508 GA, Utrecht, the Netherlands.
Br J Ophthalmol. 2007 Oct;91(10):1374-5. doi: 10.1136/bjo.2007.117903.
Currently available intraocular lenses (IOL) have widely different spectral filters. This study aimed to calculate the virtual age of IOL with regard to photoprotection and photoreception, i.e. the age of the natural lens that has similar effects on these aspects.
With diffuse solar radiation as a light source blue light damage was calculated for natural lenses at all ages, commercially available IOL and Schott steep cut-off filters in the wavelength range 300-600 nm. Similarly, the input to the short wavelength sensitive cone system was calculated for the range 380-600 nm.
The virtual age for photoprotection of IOL and steep cut-off filters varied from under 0 to 66 years. Most IOL had similar ages for photoreception, and thus show a reasonable resemblance to the spectral properties of the natural lens. Two IOL and all steep cut-off filters had a lower age for photoreception than for photoprotection, and thus outperformed the natural lens.
The virtual age of an IOL relates its spectral filtering properties to what happens in the healthy crystalline lens. Many older IOL types offer less protection than the lens of a newborn. Middle age seems a reasonable choice for an IOL.
目前可用的人工晶状体（IOL）具有广泛不同的光谱滤光片。本研究旨在计算人工晶状体在光保护和光接收方面的虚拟年龄，即对这些方面具有相似影响的天然晶状体的年龄。
以漫射太阳辐射为光源，计算了所有年龄段天然晶状体、市售人工晶状体和肖特短波截止滤光片在300 - 600 nm波长范围内的蓝光损伤。同样，在380 - 600 nm范围内计算了对短波敏感视锥系统的输入。
人工晶状体和短波截止滤光片的光保护虚拟年龄在0岁以下至66岁之间变化。大多数人工晶状体在光接收方面具有相似的年龄，因此与天然晶状体的光谱特性显示出合理的相似性。两种人工晶状体和所有短波截止滤光片在光接收方面的年龄低于光保护方面的年龄，因此优于天然晶状体。
人工晶状体的虚拟年龄将其光谱滤光特性与健康晶状体中的情况联系起来。许多较老类型的人工晶状体提供的保护比新生儿的晶状体少。中年似乎是人工晶状体的合理选择。
