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一种用于二维多动物磁共振成像的实用方法。

A practical method for 2D multiple-animal MRI.

作者信息

Ramirez Marc S, Bankson James A

机构信息

Department of Imaging Physics, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

出版信息

J Magn Reson Imaging. 2007 Oct;26(4):1162-6. doi: 10.1002/jmri.21112.

Abstract

PURPOSE

To investigate practical methods for achieving routine simultaneous 2D MRI of multiple animals in large-bore experimental scanners.

MATERIALS AND METHODS

Three four-element array geometries were compared against a standard single-coil configuration in terms of image quality, ease of use, and data efficiency using a four-channel, 4.7 T small animal imaging system.

RESULTS

A linear arrangement of volume resonators permits unobstructed animal preparation and use of an imaging protocol that is almost identical to the single-coil configuration without requiring any image correction or other additional postprocessing. Resulting in vivo images were visually indistinguishable from those acquired through the single-coil configuration.

CONCLUSION

The efficiency of animal studies employing 2D MRI techniques can be substantially improved by using a linear array of commercially available resonators.

摘要

目的

研究在大孔径实验扫描仪中实现多只动物常规同步二维磁共振成像(2D MRI)的实用方法。

材料与方法

使用四通道、4.7 T小动物成像系统,从图像质量、易用性和数据效率方面,将三种四元件阵列几何结构与标准单线圈配置进行比较。

结果

体积谐振器的线性排列允许无障碍地进行动物准备,并使用几乎与单线圈配置相同的成像方案,而无需任何图像校正或其他额外的后处理。所得的体内图像在视觉上与通过单线圈配置获取的图像无法区分。

结论

使用市售谐振器的线性阵列可大幅提高采用二维磁共振成像技术的动物研究效率。

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