Zuo Jin, Li Xiaojuan, Banerjee Suchandrima, Han Eric, Majumdar Sharmila
Musculoskeletal and Quantitative Imaging Research (MQIR), Department of Radiology, University of California, San Francisco, San Francisco, California, USA.
J Magn Reson Imaging. 2007 Oct;26(4):1001-9. doi: 10.1002/jmri.21122.
To evaluate the feasibility and reproducibility of quantitative cartilage imaging with parallel imaging at 3T and to determine the impact of the acceleration factor (AF) on morphological and relaxation measurements.
An eight-channel phased-array knee coil was employed for conventional and parallel imaging on a 3T scanner. The imaging protocol consisted of a T2-weighted fast spin echo (FSE), a 3D-spoiled gradient echo (SPGR), a custom 3D-SPGR T1rho, and a 3D-SPGR T2 sequence. Parallel imaging was performed with an array spatial sensitivity technique (ASSET). The left knees of six healthy volunteers were scanned with both conventional and parallel imaging (AF = 2).
Morphological parameters and relaxation maps from parallel imaging methods (AF = 2) showed comparable results with conventional method. The intraclass correlation coefficient (ICC) of the two methods for cartilage volume, mean cartilage thickness, T1rho, and T2 were 0.999, 0.977, 0.964, and 0.969, respectively, while demonstrating excellent reproducibility. No significant measurement differences were found when AF reached 3 despite the low signal-to-noise ratio (SNR).
The study demonstrated that parallel imaging can be applied to current knee cartilage quantification at AF = 2 without degrading measurement accuracy with good reproducibility while effectively reducing scan time. Shorter imaging times can be achieved with higher AF at the cost of SNR.
评估3T并行成像定量软骨成像的可行性和可重复性,并确定加速因子(AF)对形态学和弛豫测量的影响。
采用八通道相控阵膝关节线圈在3T扫描仪上进行传统成像和并行成像。成像方案包括T2加权快速自旋回波(FSE)、三维扰相梯度回波(SPGR)、定制的三维SPGR T1rho和三维SPGR T2序列。使用阵列空间灵敏度技术(ASSET)进行并行成像。对6名健康志愿者的左膝进行传统成像和并行成像(AF = 2)扫描。
并行成像方法(AF = 2)的形态学参数和弛豫图与传统方法显示出可比的结果。两种方法对软骨体积、平均软骨厚度、T1rho和T2的组内相关系数(ICC)分别为0.999、0.977、0.964和0.969,同时显示出良好的可重复性。尽管信噪比(SNR)较低,但当AF达到3时未发现显著的测量差异。
该研究表明,并行成像可应用于当前AF = 2时的膝关节软骨定量分析,不会降低测量准确性,具有良好的可重复性,同时有效减少扫描时间。以SNR为代价,使用更高的AF可以实现更短的成像时间。