Mühlfellner G, Mühlfellner O, Kaffarnik H
Med Klin. 1976 Apr 30;71(18):775-8.
To 9 patients with hyperlipoproteinemia type II and treated with different hypolipidemic drugs without success, sitosterol was given for a period of 4 to 16 months. The effective dose was 10.56 to 21.12g beta-sitosterol corresponding to 12 to 24g granulate. One patient developed a serious diarrhoe and dropped out. 4 patients showed an impressive decrease of serum cholesterol levels.
对于9例II型高脂蛋白血症患者,他们使用了不同的降血脂药物但均未成功,给予谷甾醇治疗4至16个月。有效剂量为10.56至21.12克β-谷甾醇,相当于12至24克颗粒剂。1例患者出现严重腹泻并退出。4例患者血清胆固醇水平显著下降。