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[β-谷甾醇治疗原发性II型高脂蛋白血症]

[Beta-sitosterin in the treatment of essential type II hyperlipoproteinemias].

作者信息

Kaffarnik H, Mühlfellner G, Mühlfellner O, Schneider J, Hausmann L, Zöfel P, Schubotz R, Fuchs F

出版信息

Fortschr Med. 1977 Dec 8;95(46):2785-7.

PMID:590905
Abstract

The effect of Beta-Sitosterol (Sitosterin Delalande) on plasma lipids in 20 pretreated patients with type IIa and IIb familial hyperlipoproteinemia is reported. 6-18 g of the drug were given for a time of two to twelve months. In 11 patients the plasma cholesterol level decreased between 10 and 30%. Since Beta-Sitosterol has no effect on plasma triglycerides, an additional hypertriglyceridemia must be taken care of and treated if necessary. Beta-Sitosterol can be called an effective substance in the treatment of hypercholesterinemia. In addition the diet cure becomes easier.

摘要

报告了β-谷甾醇(谷甾醇德拉朗德)对20例经预处理的IIa型和IIb型家族性高脂蛋白血症患者血脂的影响。给予6 - 18克该药物,持续两到十二个月。11例患者的血浆胆固醇水平下降了10%至30%。由于β-谷甾醇对血浆甘油三酯无影响,如有必要,必须关注并治疗额外的高甘油三酯血症。β-谷甾醇可被称为治疗高胆固醇血症的有效物质。此外,饮食疗法也变得更容易。

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