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真菌来源的海洋天然产物。

Marine natural products of fungal origin.

作者信息

Saleem Muhammad, Ali Muhammad Shaiq, Hussain Shafqat, Jabbar Abdul, Ashraf Muhammad, Lee Yong Sup

机构信息

Pharmaceutical Research Center, PCSIR Labs. Complex, 75280, Karachi, Pakistan.

出版信息

Nat Prod Rep. 2007 Oct;24(5):1142-52. doi: 10.1039/b607254m. Epub 2007 Mar 22.

Abstract

In the search for novel and bioactive molecules for drug discovery, marine-derived natural resources are becoming an important research area. Over 15 marine-derived secondary metabolites are currently in human clinical trials. Terrestrial fungi have produced many therapeutically significant molecules. However, the potential of marine fungi has only been investigated to a limited extent. This review article contains 103 marine-derived fungal metabolites and 77 references.

摘要

在寻找用于药物发现的新型生物活性分子的过程中,海洋来源的自然资源正成为一个重要的研究领域。目前有超过15种海洋来源的次生代谢产物正处于人体临床试验阶段。陆生真菌已经产生了许多具有治疗意义的分子。然而,海洋真菌的潜力仅在有限的程度上得到了研究。这篇综述文章包含103种海洋来源的真菌代谢产物和77篇参考文献。

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