Kleinschmidt S, Rump G, Kotter J
Abteilung für Anästhesie, Intensivmedizin und Schmerztherapie, Berufsgenossenschaftliche Unfallklinik Ludwigshafen, Ludwigshafen, Deutschland.
Anaesthesist. 2007 Dec;56(12):1257-66. doi: 10.1007/s00101-007-1264-z.
There is a great enthusiasm for herbal medications with increasing and widespread use among the population in various countries. A certain scepticism towards the use of pharmaceutical drugs may promote the use of herbal medicines such as echinacea, ginger, garlic, ginkgo, cranberry, valerian or St. John's wort even in western countries. Although considered safe among users, adverse effects such as increased bleeding tendencies, hypertension and hepatotoxicity can occur. Physicians should caution patients on the adverse side effects of herbal medicines and interactions between herbal medicines and pharmaceutical drugs, leading to various and uncontrollable deterioration of vital functions in the perioperative period. Although evidence-based data are lacking, anaesthesiologists and surgeons should be familiar with the effects of herbal medicines and should enquire about the use of these agents in the preoperative assessment. Currently available data suggest that herbal medications should be discontinued up to 2 weeks before elective surgery, although no guidelines of scientific societies have yet been published.
在各个国家，随着草药药物使用的增加和普及，人们对其热情高涨。即使在西方国家，对使用药物的某种怀疑态度也可能促使人们使用紫锥菊、生姜、大蒜、银杏、蔓越莓、缬草或圣约翰草等草药。尽管使用者认为这些草药是安全的，但仍可能出现诸如出血倾向增加、高血压和肝毒性等不良反应。医生应提醒患者注意草药的副作用以及草药与药物之间的相互作用，这些可能导致围手术期各种无法控制的重要功能恶化。尽管缺乏循证数据，但麻醉医生和外科医生应熟悉草药的作用，并应在术前评估中询问患者是否使用了这些药物。目前可得的数据表明，尽管科学协会尚未发布相关指南，但在择期手术前2周应停用草药药物。
