棘阿米巴和哈特曼氏阿米巴混合感染所致阿米巴性角膜炎的早期诊断
Early diagnosis of amoebic keratitis due to a mixed infection with Acanthamoeba and Hartmannella.
作者信息
Lorenzo-Morales Jacob, Martínez-Carretero Enrique, Batista Ninive, Alvarez-Marín Jorge, Bahaya Yasmina, Walochnik Julia, Valladares Basilio
机构信息
University Institute of Tropical Diseases and Public Health of the Canary Islands, University of La Laguna, Avda. Astrofísico Fco. Sánchez, S/N, 38203, La Laguna, Tenerife, Canary Islands, Spain.
出版信息
Parasitol Res. 2007 Dec;102(1):167-9. doi: 10.1007/s00436-007-0754-x. Epub 2007 Sep 21.
A mixed keratitis due to Acanthamoeba and Hartmannella species is reported. The patient was a soft contact lens wearer. Early diagnosis was achieved by polymerase chain reaction and culture. The pathogenic potential of the isolated amoebae was proven using cytotoxicity assays. The reported case underlines the difficulties in identifying a corneal amoebic infection. In our case, the early diagnosis of a mixed infection allowed a proper antiamoebic treatment in an early stage of infection. This may have been the reason of a successful outcome after therapy.
报告了一例由棘阿米巴属和哈特曼阿米巴属引起的混合性角膜炎。患者为软性隐形眼镜佩戴者。通过聚合酶链反应和培养实现了早期诊断。使用细胞毒性试验证明了分离出的阿米巴的致病潜力。该报告病例突显了识别角膜阿米巴感染的困难。在我们的病例中，混合感染的早期诊断使得在感染早期能够进行适当的抗阿米巴治疗。这可能是治疗后取得成功结果的原因。
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