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单纯红光光疗对寻常痤疮有效:随机单盲临床试验

Red light phototherapy alone is effective for acne vulgaris: randomized, single-blinded clinical trial.

作者信息

Na Jung Im, Suh Dae Hun

机构信息

Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.

出版信息

Dermatol Surg. 2007 Oct;33(10):1228-33; discussion 1233. doi: 10.1111/j.1524-4725.2007.33258.x.

Abstract

BACKGROUND

Recently, a demand for safe and effective treatment of acne has been increasing. Although visible light has attracted attention as a new option, the effect of red light alone has not yet been evaluated.

OBJECTIVES

The objective was to assess the efficacy of red light phototherapy with a portable device in acne vulgaris.

METHODS

Twenty-eight volunteers with mild to moderate acne were treated with portable red light-emitting devices in this split-face randomized trial. The right or left side of the face was randomized to treatment side and phototherapy was performed for 15 minutes twice a day for 8 weeks. Clinical photographs, lesion counts, and a visual analog scale (VAS) were used to assess each side of the face at baseline and Weeks 1, 2, 4, and 8, and a split-face comparison was performed.

RESULTS

The percent improvement in noninflammatory and inflammatory lesion counts of the treated side was significant compared to the control side (p<.005). VAS decreased from 3.9 to 1.9 on the treatment side and the difference between the treatment and control sides was significant at Week 8 (p<.005).

CONCLUSIONS

This study shows that red light phototherapy alone can be a new therapeutic option for acne vulgaris.

摘要

背景

最近,对痤疮安全有效治疗的需求不断增加。尽管可见光作为一种新选择已受到关注,但单独红光的效果尚未得到评估。

目的

评估使用便携式设备进行红光光疗治疗寻常痤疮的疗效。

方法

在这项半脸随机试验中,28名轻至中度痤疮志愿者接受了便携式红光发射设备的治疗。将脸的右侧或左侧随机分为治疗侧,每天进行两次15分钟的光疗,共8周。在基线以及第1、2、4和8周使用临床照片、皮损计数和视觉模拟量表(VAS)对脸的两侧进行评估,并进行半脸比较。

结果

与对照侧相比,治疗侧非炎性和炎性皮损计数的改善百分比显著(p<0.005)。治疗侧VAS从3.9降至1.9,在第8周时治疗侧与对照侧之间的差异显著(p<0.005)。

结论

本研究表明,单独的红光光疗可以成为寻常痤疮的一种新治疗选择。

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