Frithiof L, Bánóczy J
Oral Surg Oral Med Oral Pathol. 1976 May;41(5):607-22. doi: 10.1016/0030-4220(76)90313-3.
Biopsy specimens from the oral lesions of white sponge nevus (WSN) in thirteen patients were analyzed by electron microscopy. Several marked deviations from the normal ultrastructure were recorded. Similarities and dissimilarities with other hereditary disturbances affecting the epithelium are discussed. Profound disturbance of the tonofilament system, with atypical aggregation of tonofilaments, was observed. Odland bodies, which are numerous in keratinized epithelia and are extruded into the intercellular space prior to the exfoliation of the surface cells, were also abundant in the WSN specimens. Very little material originating from Odland bodies appears, however, in the intercellular space in WSN. Presumably, the Odland bodies fail to properly function enzymatically in WSN.
对13例白色海绵状痣（WSN）口腔损害的活检标本进行了电子显微镜分析。记录到一些与正常超微结构明显不同的情况。讨论了与其他影响上皮的遗传性疾病的异同。观察到张力丝系统有严重紊乱，伴有张力丝的非典型聚集。奥尔德体在角化上皮中数量众多，在表面细胞脱落前被挤入细胞间隙，在WSN标本中也很丰富。然而，在WSN的细胞间隙中，来自奥尔德体的物质很少出现。推测奥尔德体在WSN中未能正常发挥酶促功能。
