Simon Joel A, Tanzman Jay S, Sabaté Joan
General Internal Medicine (111A1), San Francisco VA Medical Center, 4150 Clement Street, San Francisco, California 94121, USA.
J Am Coll Nutr. 2007 Aug;26(4):317-20. doi: 10.1080/07315724.2007.10719617.
To examine whether the short-term consumption of walnuts, a food rich in alpha-linolenic acid, affects levels of serum prostate-specific antigen (PSA), a marker of prostate enlargement, inflammation, and cancer.
Using data from a 12-month randomized crossover study examining the effect of walnut consumption on body composition, we examined whether increased walnut consumption (mean 35 grams daily, 12% total energy) affected serum PSA levels among 40 middle-aged men.
There was no significant difference between mean PSA level at the conclusion of the 6-month walnut-supplemented diet (1.05 mug/L, 95% CI [0.81, 1.37]) and the conclusion of the 6-month control diet (1.06 mug/L, 95% CI [0.81, 1.38]) (P = 0.86) (or a mean proportional decrease in PSA of -1%).
Our results suggest that short-term consumption of walnuts is unlikely to affect PSA levels adversely among otherwise normal men.
研究短期食用富含α-亚麻酸的核桃是否会影响血清前列腺特异性抗原（PSA）水平，PSA是前列腺肿大、炎症及癌症的一个标志物。
利用一项为期12个月的随机交叉研究的数据，该研究探讨食用核桃对身体成分的影响，我们研究了核桃摄入量增加（平均每日35克，占总能量的12%）是否会影响40名中年男性的血清PSA水平。
在为期6个月的核桃补充饮食结束时，平均PSA水平为1.05微克/升，95%置信区间为[0.81, 1.37]；在为期6个月的对照饮食结束时，平均PSA水平为1.06微克/升，95%置信区间为[0.81, 1.38]，两者之间无显著差异（P = 0.86）（或PSA平均比例下降-1%）。
我们的结果表明，在其他方面正常的男性中，短期食用核桃不太可能对PSA水平产生不利影响。
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