Cai Rong-lin, Hu Ling, Zhou Yi-ping, Wu Zi-jian, Wang Ke-ming, Tang Xiao-min, Li Meng, Li Zi-hui
Institute of Acu-Moxibustion and Meridians, Anhui College of Chinese Medicine, Hefei, China.
Zhen Ci Yan Jiu. 2007 Aug;32(4):243-6.
To observe the effect of electroacupuncture (EA) of "Shenmen" (HT 7) and "Zhizheng" (SI 7) on cardiac function and electrical activities of the cardiac sympathetic nerve in acute myocardial schemia rabbits.
Forty livid-blue rabbits were randomly divided into normal control, model, "Shenmen" (HT 7) and "Zhizheng" (517) groups with 10 cases in each group. Acute myocardial ischemia (AMI) model was established by intravenous injection of pituitrin (3 U/kg). Changes of heart rate (HR), maximum rising rate (+dp/dt max) and maximum descending rate (-dp/dt max) of the left ventricular systolic pressure (LVSP), and discharges of cardiac sympathetic nerve (superior cardiac branch) were recorded. EA (2 Hz, 5 V) was applied to bilateral "Shenmen" (HT 7) and "Zhizheng" (SI 7) for 30 mm.
After AMI, HR, LVSP, +dp/dt max and firing frequency of cardiac sympathetic nerve decreased significantly (P < 0.01), and -dp/dt max increased obviously in model group (P < 0.01). Compared with model group, HR, +dp/dt max and cardiac sympathetic discharge of HT7 and S17 groups increased significantly 10 mm and 20 mm after EA (P < 0.05, 0.01), and -dp/dt max of the later 2 groups reduced evidently 20 mm after EA (P < 0.05, 0.01). No significant differences were found between HT7 and control groups in HR, LVSP and the firing frequency of cardiac nerve 20 mm and 30 mm after EA, and between S17 and control groups in the firing frequency of cardiac nerve 30 mm after EA (P > 0.05). The effects of group HT7 were significantly better than those of S17 (P < 0.05).
EA of both HT7 and S17 can obviously improve cardiac function and electrical activity of cardiac sympathetic nerve in AMI, and the effects of HT7 are markedly better than those of S17.
观察电针“神门”（HT 7）和“支正”（SI 7）对急性心肌缺血家兔心功能及心脏交感神经电活动的影响。
将40只青紫蓝兔随机分为正常对照组、模型组、“神门”（HT 7）组和“支正”（SI 7）组，每组10只。通过静脉注射垂体后叶素（3 U/kg）建立急性心肌缺血（AMI）模型。记录心率（HR）、左心室收缩压（LVSP）的最大上升速率（+dp/dt max）和最大下降速率（-dp/dt max）以及心脏交感神经（心上级分支）的放电情况。以2 Hz、5 V的频率对双侧“神门”（HT 7）和“支正”（SI 7）进行电针刺激30分钟。
AMI后，模型组HR、LVSP、+dp/dt max及心脏交感神经放电频率显著降低（P < 0.01），-dp/dt max明显升高（P < 0.01）。与模型组比较，电针后10分钟和20分钟，HT 7组和SI 7组的HR、+dp/dt max及心脏交感神经放电显著增加（P < 0.05，0.01），后两组的-dp/dt max在电针后20分钟明显降低（P < 0.05，0.01）。电针后20分钟和30分钟，HT 7组与对照组在HR、LVSP及心脏神经放电频率方面无显著差异，电针后30分钟，SI 7组与对照组在心脏神经放电频率方面无显著差异（P > 0.05）。HT 7组的效果明显优于SI 7组（P < 0.05）。
电针HT 7和SI 7均能明显改善AMI家兔的心功能及心脏交感神经电活动，且HT 7组效果明显优于SI 7组。
