Luan De Chun, Li Hui, Li Sui Jing, Zhao Zhuo, Li Xin, Liu Zhong Mei
Institute for Nutrition and Food Safety, Liaoning Provincial Center for Disease Control and Prevention, 42-1 Ji Xian St., Shenyang 110005, China.
Diabetes Care. 2008 Feb;31(2):285-6. doi: 10.2337/dc07-0921. Epub 2007 Oct 1.
To evaluate the association between body iron stores, dietary iron intake, and risk of diabetes in northern China.
The data of a cross-sectional household survey in 2002 in Liaoning Province in northern China was used. The final sample in our study contained 2,997 subjects aged >or=18 years. Fasting plasma glucose and serum ferritin were measured. Dietary information was collected by 3-day food records.
Serum ferritin was associated with elevated risk of diabetes even adjusted for age, sex, nondietary factors, and dietary factors. No association among total iron intake, nonheme iron intake, and diabetes risk was found. However, higher heme iron intake was significantly associated with elevated risk of diabetes after adjusting for known factors.
In Chinese, associations among higher serum ferritin level, higher heme iron intake, and elevated risk of diabetes were found.
评估中国北方人群体内铁储备、膳食铁摄入量与糖尿病风险之间的关联。
采用2002年在中国北方辽宁省进行的一项横断面家庭调查数据。本研究的最终样本包含2997名年龄≥18岁的受试者。测量空腹血糖和血清铁蛋白。通过3天食物记录收集饮食信息。
即使在调整年龄、性别、非饮食因素和饮食因素后，血清铁蛋白仍与糖尿病风险升高相关。未发现总铁摄入量、非血红素铁摄入量与糖尿病风险之间存在关联。然而，在调整已知因素后，较高的血红素铁摄入量与糖尿病风险升高显著相关。
在中国人群中，发现较高的血清铁蛋白水平、较高的血红素铁摄入量与糖尿病风险升高之间存在关联。
