Sobotka Lubos, Smahelova Alena, Pastorova Jana, Kusalova Marie
Department of Metabolic Care and Gerontology, Medical Faculty, Charles University, Hradec Kralove, Czech Republic. pustik@lfhk. cuni.cz
Int J Low Extrem Wounds. 2007 Sep;6(3):143-7. doi: 10.1177/1534734607304684.
Diabetic foot ulcers are difficult to heal due to defects in local microvasculature and persistent, concomitant infection. Despite the best medical care, amputation is often a management option for this problem. The authors have developed a new and unique system for wound treatment, which is based on a combination of high molecular weight sodium hyaluronate with an iodine complex-Hyiodine (Contipro C, Dolní Dobrouc, Czech Republic). In this case report, the authors present an observational study on a series of patients with diabetic foot disease with nonhealing wounds treated with Hyiodine. The effect of the HA-iodine complex was studied on 18 patients suffering from complicated foot diabetic wounds. The HA-iodine complex was either spread directly over the wound, or more frequently, gauze was immersed in the HA-iodine complex and then put on/into the wound. Then several layers of dry gauze covered the wound. This dressing was changed every 24 hours. Wound healing was monitored daily, and wound pictures were taken each second week. Clinical improvement was observed in the majority. This suggests that the HA-iodine complex dressing has potential that needs to be developed from controlled studies.
糖尿病足溃疡因局部微血管缺陷和持续伴随感染而难以愈合。尽管给予了最佳医疗护理,但截肢往往是解决这一问题的一种治疗选择。作者开发了一种全新且独特的伤口治疗系统,该系统基于高分子量透明质酸钠与碘复合物——海碘定(Contipro C,捷克共和国多尔尼多布罗乌采)的组合。在本病例报告中,作者呈现了一项对一系列患有糖尿病足病且伤口不愈合的患者使用海碘定进行治疗的观察性研究。研究了透明质酸 - 碘复合物对18例患有复杂性足部糖尿病伤口患者的疗效。透明质酸 - 碘复合物要么直接涂抹在伤口上,或者更常见的是,将纱布浸泡在透明质酸 - 碘复合物中,然后敷在伤口上/放入伤口内。接着用几层干纱布覆盖伤口。这种敷料每24小时更换一次。每天监测伤口愈合情况,每隔一周拍摄伤口照片。大多数患者观察到临床改善。这表明透明质酸 - 碘复合物敷料具有有待通过对照研究进一步开发的潜力。