软海绵腈，一种来自软海绵属菌株A59 - 96的新型抗生素。
Mollisianitrile, a new antibiotic from Mollisia sp. A59-96.
作者信息
Weber Daniela, Sterner Olov, Anke Timm
机构信息
a Institut für Biotechnologie und Wirkstoff-Forschung IBWF e.V., Erwin-Schrödinger-Strasse 56, D-67663 Kaiserslautern, Germany.
出版信息
Z Naturforsch C J Biosci. 2007 Jul-Aug;62(7-8):567-70. doi: 10.1515/znc-2007-7-817.
Mollisianitrile (1), a new antibiotic was isolated from the fermentation broth of Mollisa sp. A59-96 together with the two known isocoumarins 2 and 3. 1 exhibited antimicrobial, cytotoxic, and phytotoxic activities. 1 contains a reactive propiolonitrile moiety which is believed to be responsible for its antibiotic activities. Upon incubation with L-cysteine the biological activity was lost.
莫利腈（1）是从莫利萨菌属A59 - 96的发酵液中分离出的一种新型抗生素，同时还分离出了两种已知的异香豆素2和3。1具有抗菌、细胞毒性和植物毒性活性。1含有一个活性丙炔腈部分，据信这是其抗生素活性的原因。与L-半胱氨酸孵育后，生物活性丧失。
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