Palm Noah W, Medzhitov Ruslan
Nat Med. 2007 Oct;13(10):1142-4. doi: 10.1038/nm1007-1142b.
The innate and adaptive immune systems act in concert to effectively combat infection while minimizing collater al damage caused by the host immune response. T cells of the adaptive immune system have now been shown to suppress overzealous early innate responses to infection that can lead to 'cytokine storm'–mediated death (pages 1248–1252).
先天性免疫系统和适应性免疫系统协同作用,有效对抗感染,同时将宿主免疫反应造成的附带损害降至最低。现已证明,适应性免疫系统的T细胞可抑制对感染过度强烈的早期先天性反应,这种反应可能导致“细胞因子风暴”介导的死亡(第1248 - 1252页)。