1993年至2001年荷兰结核病患者中与艾滋病病毒相关的死亡率
HIV-related mortality among tuberculosis patients in The Netherlands, 1993-2001.
作者信息
Haar C H, Cobelens F G J, Kalisvaart N A, van Gerven P J H J, van der Have J J
机构信息
KNCV Tuberculosis Foundation, The Hague, The Netherlands.
出版信息
Int J Tuberc Lung Dis. 2007 Sep;11(9):1038-41.
Human immunodeficiency virus (HIV) infection in tuberculosis (TB) patients in The Netherlands during the period 1993-2001 was associated with an increased risk of death (adjusted odds ratio 4.71, P < 0.002). Age and sex-standardised mortality rates among HIV-infected TB patients decreased significantly over time, from 22.9% in 1993-1995 to 11.8% in 1999-2001 (P < 0.001). No such change was observed for HIV-negative patients. The decrease in mortality is likely due to the more widespread use of highly active antiretroviral therapy (HAART).
1993年至2001年期间，荷兰结核病（TB）患者中的人类免疫缺陷病毒（HIV）感染与死亡风险增加相关（调整后的优势比为4.71，P<0.002）。随着时间的推移，HIV感染的结核病患者中按年龄和性别标准化的死亡率显著下降，从1993 - 1995年的22.9%降至1999 - 2001年的11.8%（P<0.001）。HIV阴性患者未观察到此类变化。死亡率的下降可能归因于高效抗逆转录病毒疗法（HAART）的更广泛使用。
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