Lara-Villoslada Federico, Olivares Mónica, Sierra Saleta, Rodríguez Juan Miguel, Boza Julio, Xaus Jordi
Nutrition and Health Department, Puleva Biotech. Cno, De Purchil no 66, 18004, Granada, Spain.
Br J Nutr. 2007 Oct;98 Suppl 1:S96-100. doi: 10.1017/S0007114507832910.
Breast milk is the best food for the neonate because it provides a unique combination of proteins, carbohydrates, lipids, minerals and vitamins that ensures the correct growth and development of the infant. In addition, it also contains bioactive compounds responsible for a wide range of beneficial effects such as the promotion of immune system maturation and the protection against infections. Among these bioactive agents, probiotic bacteria have been recently isolated from human milk. The present work reviews the beneficial effects of these bacteria both in animal models and in clinical trials. The promotion of immune system maturation and defence against infections as well as the anti-inflammatory properties are among the main healthy effects of these bacteria. The isolation of probiotic bacteria with beneficial effects for the host provides scientific support for the supplementation of infant formula with these bacteria, in order to advance the pursuit of the main goal of formula: to mimic breast milk and its functional effects as closely as possible.
母乳是新生儿的最佳食物,因为它提供了蛋白质、碳水化合物、脂质、矿物质和维生素的独特组合,确保婴儿的正常生长和发育。此外,它还含有生物活性化合物,这些化合物具有广泛的有益作用,如促进免疫系统成熟和预防感染。在这些生物活性物质中,益生菌最近已从人乳中分离出来。本研究综述了这些细菌在动物模型和临床试验中的有益作用。促进免疫系统成熟、抵御感染以及抗炎特性是这些细菌的主要健康益处。分离出对宿主有益的益生菌为在婴儿配方奶粉中添加这些细菌提供了科学依据,以便更接近实现配方奶粉的主要目标:尽可能模仿母乳及其功能作用。