Mick Eric, Faraone Stephen V, Spencer Thomas, Zhang Huabin F, Biederman Joseph
Massachusetts General Hospital, Pediatric Psychopharmacology Research Unit, Boston MA 02114, USA.
J Atten Disord. 2008 Jan;11(4):504-9. doi: 10.1177/1087054707308468. Epub 2007 Oct 12.
The authors assessed the psychometric properties of the Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form (Q-LES-QSF) in adults with ADHD.
One hundred fifty ADHD and 134 non-ADHD adults from a case-control study and 173 adults randomized to placebo or methylphenidate were assessed with the Q-LES-QSF and the Social Adjustment Scale (SAS). Response to change was estimated by comparing change in Q-LES-QSF scores in responders and nonresponders in our randomized clinical trial.
Internal consistency of the Q-LES-QSF items was .88, and the correlation between the Q-LES-QSF total score and the SAS total T score was .72 in adults with ADHD. ADHD cases had statistically significantly poorer scores on the Q-LES-QSF than controls (76.5 +/- 10.9 vs. 59.2 +/- 17.3, p < .001), whereas ADHD responders showed Q-LES-QSF improvement compared to nonresponders (76.1 +/- 12.0 versus 67.9 +/- 14.5, p < .001).
These results support the validity of the Q-LES-QSF as a measure of quality of life in adults with ADHD.
作者评估了成人注意力缺陷多动障碍(ADHD)患者生活质量享受与满意度问卷简表(Q-LES-QSF)的心理测量特性。
对来自一项病例对照研究的150名ADHD成人和134名非ADHD成人,以及173名随机分配接受安慰剂或哌甲酯治疗的成人,使用Q-LES-QSF和社会适应量表(SAS)进行评估。通过比较我们随机临床试验中反应者和无反应者Q-LES-QSF分数的变化来估计对变化的反应。
ADHD成人中,Q-LES-QSF项目的内部一致性为0.88,Q-LES-QSF总分与SAS总T分之间的相关性为0.72。ADHD病例在Q-LES-QSF上的得分在统计学上显著低于对照组(76.5±10.9对59.2±17.3,p<0.001),而ADHD反应者与无反应者相比,Q-LES-QSF有所改善(76.1±12.0对67.9±14.5,p<0.001)。
这些结果支持Q-LES-QSF作为ADHD成人生活质量测量工具的有效性。