Fatahzadeh Mahnaz, Schwartz Robert A
Department of Oral Medicine, New Jersey Dental School, Newark, New Jersey 07103, USA.
J Am Acad Dermatol. 2007 Nov;57(5):737-63; quiz 764-6. doi: 10.1016/j.jaad.2007.06.027.
Eight of the more than 80 known herpesviruses are human pathogens. Human herpes simplex virus (HSV) is a contagious infection with a large reservoir in the general population. It has a potential for significant complications in the immunocompromised host. In addition, psychological distress caused by the negative stigma associated with genital herpes and visible facial lesions in those experiencing frequent outbreaks renders it a challenging clinical dilemma. This article reviews the epidemiology, pathogenesis, and diagnostic features of HSV infections, providing the clinician with an up-to-date understanding of the available management strategies for mucocutaneous HSV-induced disease.
80多种已知的疱疹病毒中有8种是人类病原体。人类单纯疱疹病毒（HSV）是一种具有传染性的感染，在普通人群中有大量宿主。它在免疫功能低下的宿主中有可能引发严重并发症。此外，生殖器疱疹带来的负面污名以及频繁发作的患者面部可见病变所导致的心理困扰，使其成为一个具有挑战性的临床难题。本文综述了HSV感染的流行病学、发病机制和诊断特征，为临床医生提供了对黏膜皮肤HSV诱发疾病现有管理策略的最新认识。
