Karapanagiotou Elena, Saif Muhammad Wasif, Rondoyianni Dimitra, Markaki Sofia, Alamara Christina, Kiagia Maria, Pantazopoulos Kosmas, Tzannou Ifigenia, Syrigos Kostas
Oncology Unit, Third Department of Medicine, Athens School of Medicine, Sotiria General Hospital, Athens, Greece.
Yale J Biol Med. 2006 Dec;79(3-4):165-8.
Although metastases within the thyroid gland are rare, they are not as infrequent as generally believed. Asymptomatic breast, lung, and renal cell carcinomas may metastasize to the thyroid. When they become symptomatic, diagnosis relies upon fine needle aspiration cytology. We report the case of a squamous cell cervical cancer that presented metastatic lesions to the thyroid gland four years after the initial diagnosis. The procedures used to confirm the diagnosis, stage, and subsequently manage the patient are described. We present both a review of the necessary clinical investigation and the therapeutic options open to these patients. We conclude that patients who present swelling or palpable nodules in the thyroid side and have a history of a previous malignancy must be considered for metastatic disease.
尽管甲状腺内转移很少见,但并不像普遍认为的那样罕见。无症状的乳腺癌、肺癌和肾细胞癌可能转移至甲状腺。出现症状时,诊断依赖于细针穿刺细胞学检查。我们报告一例宫颈鳞状细胞癌病例,该患者在初次诊断四年后出现甲状腺转移瘤。描述了用于确诊、分期及后续治疗该患者的程序。我们对必要的临床检查及这些患者可采用的治疗方案进行了综述。我们得出结论,对于甲状腺侧出现肿胀或可触及结节且有既往恶性肿瘤病史的患者,必须考虑转移性疾病。