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宫颈癌的甲状腺转移:对临床医生的异常启示——病例报告

Thyroid metastases from cervical carcinoma: unusual implications for clinicians-case report.

作者信息

Yang Qian, Yan Weipeng, Wang Ning, Xu Pengfei, Huang Qing

机构信息

Department of Radiology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Department of Pathology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

BMC Endocr Disord. 2024 Dec 20;24(1):273. doi: 10.1186/s12902-024-01814-y.

Abstract

BACKGROUND

Thyroid metastases from uterine cervical carcinoma are exceedingly rare. Imaging examination and pathological detection exert a pivotal function in distinguishing between benign and malignant thyroid tumors, as well as differentiating metastases from primary thyroid cancer.

CASE PRESENTATION

Here, we present two cases of uterine cervical cancer metastasizing to the thyroid gland, confirmed by postoperative histopathology at our hospital. Furthermore, we conduct a comprehensive analysis of the imaging appearances, pathological characteristics, diagnosis, prognosis and treatment of the disease through a review of relevant literature. The two cases do not exhibit specific laboratory indicators, making imaging examinations important auxiliary tools, while pathology remains the gold standard for diagnosis.

CONCLUSIONS

Although thyroid malignancies predominantly arise as primary tumors, it's crucial to consider the possibility of metastases in patients with a history of cancer. Metastases to the thyroid are relatively uncommon but can occur, particularly in advanced stages of other cancers. Poor outcomes of thyroid metastases from cervical carcinoma have presented significant hurdles for clinicians. Surgical excision of metastatic thyroid cancer may serve as an alternative, offering relief from compression symptoms and prolonging survival to some extent. Further studies are crucially needed to optimize clinical outcomes of the disease.

摘要

背景

子宫颈癌的甲状腺转移极为罕见。影像学检查和病理检测在区分甲状腺良性和恶性肿瘤以及鉴别原发性甲状腺癌转移方面发挥着关键作用。

病例介绍

在此,我们报告我院术后组织病理学确诊的两例子宫颈癌转移至甲状腺的病例。此外,我们通过回顾相关文献,对该疾病的影像学表现、病理特征、诊断、预后及治疗进行了综合分析。这两例病例未表现出特异性实验室指标,使影像学检查成为重要的辅助工具,而病理检查仍是诊断的金标准。

结论

尽管甲状腺恶性肿瘤主要为原发性肿瘤,但对于有癌症病史的患者,考虑转移的可能性至关重要。甲状腺转移相对少见,但可能发生,尤其是在其他癌症的晚期。子宫颈癌甲状腺转移的不良预后给临床医生带来了重大障碍。手术切除转移性甲状腺癌可能是一种选择,可缓解压迫症状并在一定程度上延长生存期。迫切需要进一步研究以优化该疾病的临床治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/06cd/11662705/62f8dccf18ae/12902_2024_1814_Fig1_HTML.jpg

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