Benlyazid Adil, Lacroix-Triki Magali, Aziza Richard, Gomez-Brouchet Anne, Guichard Maryalis, Sarini Jérôme
Department of Head and Neck Surgery, Institut Claudius Regaud, Toulouse, France.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Dec;104(6):e17-24. doi: 10.1016/j.tripleo.2007.05.026. Epub 2007 Oct 17.
A case of ameloblastic carcinoma of the maxilla arising in a 90-year-old patient is presented along with a review of 65 other cases of the international literature.
The median age was 44 years with a predominance of men (42/66). The maxilla was concerned in almost one third of cases (21/66). Twenty patients died of disease after a median time of 60 months. Fifteen patients died with metastatic spread in the lung, brain, or bones; the others were due to a local recurrence. The specific survival rate was 68.7% at 5 years.
Ameloblastic carcinoma is a rare entity of odontogenic tumors that exhibits malignant histologic features in the primary site. Specific mortality, estimated at 31.3% at 5 years, was generally due to a metastatic spread.
本文报告了1例90岁上颌骨成釉细胞癌患者的病例，并对国际文献中其他65例病例进行了回顾。
中位年龄为44岁，男性居多（42/66）。近三分之一的病例（21/66）累及上颌骨。20例患者在中位时间60个月后死于该疾病。15例患者因肺、脑或骨转移扩散死亡；其他患者死于局部复发。5年的特定生存率为68.7%。
成釉细胞癌是一种罕见的牙源性肿瘤，在原发部位表现出恶性组织学特征。5年的特定死亡率估计为31.3%，通常是由于转移扩散所致。
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