成釉细胞瘤恶变：18 例临床病理分析及系统评价
Ameloblastic carcinoma: Clinicopathological analysis of 18 cases and a systematic review.
机构信息
Nursing School, Guizhou University of Traditional Chinese Medicine, Guiyang, China.
State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
出版信息
Head Neck. 2019 Dec;41(12):4191-4198. doi: 10.1002/hed.25926. Epub 2019 Aug 24.
OBJECTIVES
Exploring the clinicopathological features of ameloblastic carcinoma (AC) and reviewing the literature to improve the diagnosis and treatment of the disease.
MATERIALS AND METHODS
Clinical data and pathological features of 18 cases of AC were retrospectively analyzed. A systematic review was carried out by searching PubMed and Medline databases using the MeSH terms "ameloblastic" and "carcinoma."
RESULTS
In the systematic analysis, 125 cases of AC from 81 eligible original studies and 18 cases of AC from this research were included. The male-to-female ratio was 2.58:1, and the mandible-to-maxilla ratio was 1.80:1. Mean age of patients was 45.3 years. Thirty-seven cases of recurrence and 27 cases of metastasis were recorded.
CONCLUSION
AC is a rare neoplasm of the odontogenic epithelium. A systematic review indicates that diagnoses at the early phase and a close periodic assessment for recurrence and metastasis are necessary.
目的
探讨成釉细胞瘤（AC）的临床病理特征，复习文献以提高对该病的诊断和治疗水平。
材料与方法
回顾性分析 18 例 AC 的临床资料和病理特征。通过使用 MeSH 术语“成釉细胞瘤”和“癌”，在 PubMed 和 Medline 数据库中进行系统评价。
结果
在系统分析中，纳入了 81 项符合条件的原始研究中的 125 例 AC 病例和本研究中的 18 例 AC 病例。男女比例为 2.58:1，下颌骨与上颌骨的比例为 1.80:1。患者的平均年龄为 45.3 岁。记录了 37 例复发和 27 例转移。
结论
AC 是一种罕见的牙源性上皮性肿瘤。系统评价表明，早期诊断和密切定期评估复发和转移是必要的。
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