在一例钩端螺旋体病致死病例中对人组织和环境样本进行问号钩端螺旋体的分子检测。

Molecular detection of Leptospira interrogans in human tissues and environmental samples in a lethal case of leptospirosis.

作者信息

Luchini D, Meacci F, Oggioni M R, Morabito G, D'Amato V, Gabbrielli M, Pozzi G

机构信息

Department of Forensic Sciences, University of Siena, Policlinico Le Scotte, Viale Bracci, 53100 Siena, Italy.

出版信息

Int J Legal Med. 2008 May;122(3):229-33. doi: 10.1007/s00414-007-0212-4. Epub 2007 Oct 18.

DOI:10.1007/s00414-007-0212-4

PMID:17943302

Abstract

A forensic case of suspected Leptospirosis with fatal course was resolved by the molecular detection of Leptospira interrogans in postmortem human tissues and in environmental samples. Polymerase chain reaction analysis and DNA sequencing confirmed the clinical diagnosis of Weil syndrome, and the death was considered to be an occupational accident with all the legal implications.

摘要

一例疑似钩端螺旋体病致死的法医案件，通过在人体尸检组织和环境样本中对问号钩端螺旋体进行分子检测得以解决。聚合酶链反应分析和DNA测序证实了韦尔综合征的临床诊断，该死亡被认定为一起具有所有法律后果的职业事故。