Keeling A N, Leong S, Logan P M, Lee M J
Department of Academic Radiology, Beaumont Hospital, Dublin 9, Ireland.
Cardiovasc Intervent Radiol. 2008 Jan-Feb;31(1):135-41. doi: 10.1007/s00270-007-9197-0. Epub 2007 Oct 18.
Empyema and complicated pleural effusion represent common medical problems. Current treatment options are multiple. The purpose of this study was to access the outcome of image-guided, small-bore catheter drainage of empyema and effusion. We evaluated 93 small-bore catheters in 82 patients with pleural effusion (n = 30) or empyema (n = 52), over a 2-year period. Image guidance was with ultrasound (US; n = 56) and CT (n = 37). All patients were followed clinically, with catheter dwell times, catheter outcome, pleural fluid outcome, reinsertion rates, and need for urokinase or surgery recorded. Ninety-three small-bore chest drains (mean=10.2 Fr; range, 8.2-12.2 Fr) were inserted, with an average dwell time of 7.81 days for empyemas and 7.14 days for effusions (p > 0.05). Elective removal rates (73% empyema vs 86% effusions) and dislodgement rates (12% empyema vs 13% effusions) were similar for both groups. Eight percent of catheters became blocked and 17% necessitated reinsertion in empyemas, with no catheters blocked or requiring reinsertion in effusions (p < 0.05). Thirty-two patients (51%) required urokinase in the empyema group, versus 2 patients (6%) in the effusion group (p < 0.05). All treatment failures, requiring surgery, occurred in the empyema group (19%; n = 12; p < 0.05). In conclusion, noninfected pleural collections are adequately treated with small-bore catheters, however, empyemas have a failure rate of 19%. The threshold for using urokinase and larger-bore catheters should be low in empyema.
脓胸和复杂性胸腔积液是常见的医学问题。目前的治疗选择多种多样。本研究的目的是评估影像引导下小口径导管引流脓胸和积液的效果。在两年期间,我们对82例胸腔积液(n = 30)或脓胸(n = 52)患者的93根小口径导管进行了评估。影像引导采用超声(US;n = 56)和CT(n = 37)。对所有患者进行临床随访,记录导管留置时间、导管结局、胸腔积液结局、重新插入率以及是否需要使用尿激酶或进行手术。共插入93根小口径胸腔引流管(平均10.2 Fr;范围8.2 - 12.2 Fr),脓胸的平均留置时间为7.81天,积液的平均留置时间为7.14天(p > 0.05)。两组的择期拔除率(脓胸为73%,积液为86%)和移位率(脓胸为12%,积液为13%)相似。脓胸组有8%的导管堵塞,17%需要重新插入,而积液组无导管堵塞或需要重新插入的情况(p < 0.05)。脓胸组有32例患者(51%)需要使用尿激酶,而积液组为2例患者(6%)(p < 0.05)。所有需要手术的治疗失败病例均发生在脓胸组(19%;n = 12;p < 0.05)。总之,非感染性胸腔积液用小口径导管治疗效果良好,然而,脓胸的失败率为19%。在脓胸治疗中,使用尿激酶和更大口径导管的阈值应该较低。