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脓胸与胸腔积液:影像引导下细针导管引流的结果

Empyema and effusion: outcome of image-guided small-bore catheter drainage.

作者信息

Keeling A N, Leong S, Logan P M, Lee M J

机构信息

Department of Academic Radiology, Beaumont Hospital, Dublin 9, Ireland.

出版信息

Cardiovasc Intervent Radiol. 2008 Jan-Feb;31(1):135-41. doi: 10.1007/s00270-007-9197-0. Epub 2007 Oct 18.

Abstract

Empyema and complicated pleural effusion represent common medical problems. Current treatment options are multiple. The purpose of this study was to access the outcome of image-guided, small-bore catheter drainage of empyema and effusion. We evaluated 93 small-bore catheters in 82 patients with pleural effusion (n = 30) or empyema (n = 52), over a 2-year period. Image guidance was with ultrasound (US; n = 56) and CT (n = 37). All patients were followed clinically, with catheter dwell times, catheter outcome, pleural fluid outcome, reinsertion rates, and need for urokinase or surgery recorded. Ninety-three small-bore chest drains (mean=10.2 Fr; range, 8.2-12.2 Fr) were inserted, with an average dwell time of 7.81 days for empyemas and 7.14 days for effusions (p > 0.05). Elective removal rates (73% empyema vs 86% effusions) and dislodgement rates (12% empyema vs 13% effusions) were similar for both groups. Eight percent of catheters became blocked and 17% necessitated reinsertion in empyemas, with no catheters blocked or requiring reinsertion in effusions (p < 0.05). Thirty-two patients (51%) required urokinase in the empyema group, versus 2 patients (6%) in the effusion group (p < 0.05). All treatment failures, requiring surgery, occurred in the empyema group (19%; n = 12; p < 0.05). In conclusion, noninfected pleural collections are adequately treated with small-bore catheters, however, empyemas have a failure rate of 19%. The threshold for using urokinase and larger-bore catheters should be low in empyema.

摘要

脓胸和复杂性胸腔积液是常见的医学问题。目前的治疗选择多种多样。本研究的目的是评估影像引导下小口径导管引流脓胸和积液的效果。在两年期间,我们对82例胸腔积液(n = 30)或脓胸(n = 52)患者的93根小口径导管进行了评估。影像引导采用超声(US;n = 56)和CT(n = 37)。对所有患者进行临床随访,记录导管留置时间、导管结局、胸腔积液结局、重新插入率以及是否需要使用尿激酶或进行手术。共插入93根小口径胸腔引流管(平均10.2 Fr;范围8.2 - 12.2 Fr),脓胸的平均留置时间为7.81天,积液的平均留置时间为7.14天(p > 0.05)。两组的择期拔除率(脓胸为73%,积液为86%)和移位率(脓胸为12%,积液为13%)相似。脓胸组有8%的导管堵塞,17%需要重新插入,而积液组无导管堵塞或需要重新插入的情况(p < 0.05)。脓胸组有32例患者(51%)需要使用尿激酶,而积液组为2例患者(6%)(p < 0.05)。所有需要手术的治疗失败病例均发生在脓胸组(19%;n = 12;p < 0.05)。总之,非感染性胸腔积液用小口径导管治疗效果良好,然而,脓胸的失败率为19%。在脓胸治疗中,使用尿激酶和更大口径导管的阈值应该较低。

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