Mahmood Ansar, Zafar Mohammed S, Majid Ibrar, Maffulli Nicola, Thompson John
Department of Trauma and Orthopaedic Surgery, Keele University School of Medicine Thornburrow Drive, Hartshill, Stoke on Trent, Staffordshire ST4 7QB, UK.
Br Med Bull. 2007;84:37-48. doi: 10.1093/bmb/ldm029. Epub 2007 Oct 23.
To perform a comprehensive quantitative review of the published literature and to assess the methodology of studies comparing the surgical outcomes in minimally invasive hip arthroplasty (MIHA).
We conducted a comprehensive literature search using Medline, Embase, Cochrane, CINAHL and Google Scholar. The bibliographies of papers were also examined. All relevant articles in peer-reviewed journals were retrieved except those not mentioning outcomes, case reports, review of literature and letters to editors. Two authors independently scored the quality of the studies using a modified Coleman Methodology Score with 10 criteria which allow critical analysis of the design and implementation of a particular study. The results are recorded as a final score between 0 and 100. We collected data for year of publication, type of study, patient numbers, surgical method, follow-up, complications and patient satisfaction.
Thirty-six studies met our inclusion criteria giving details of 6434 HAs, 78.5% (4031) of which were implanted using MIHA techniques. The only statistically significant outcome was a reduction in length of hospital stay (P = 0.02). With no significant difference noted between the two groups with respect to operating time, blood loss, dislocation and revision rates, neurological injury and incidence of peri-operative fracture, patient selection and surgeons' experience may have had a significant effect on outcome. For instance, studies reporting outcomes on an average patient age of 48 years had significantly different results to one reporting on patients with a mean age of over 70 years. Scores were predominantly low for quality of the studies, with patient number, follow-up time and validated outcome measures being the weakest areas.
At present, there is still a lack of quality evidence to advocate the expansion of MIHA. The better designed studies suggest that it should even be limited further to recognized expert centres. The complication rates and learning curve may be altered by changes in training and adapting surgical techniques. We emphasize the need for meticulous design in future studies comparing the outcomes of these two procedures.
对已发表的文献进行全面的定量综述,并评估比较微创髋关节置换术(MIHA)手术效果的研究方法。
我们使用Medline、Embase、Cochrane、CINAHL和谷歌学术进行了全面的文献检索。还检查了论文的参考文献。检索了同行评审期刊中的所有相关文章,但不包括未提及结果的文章、病例报告、文献综述和给编辑的信件。两位作者使用修改后的科尔曼方法评分对研究质量进行独立评分,该评分有10项标准,可对特定研究的设计和实施进行批判性分析。结果记录为0至100之间的最终分数。我们收集了发表年份、研究类型、患者数量、手术方法、随访、并发症和患者满意度的数据。
36项研究符合我们的纳入标准,详细介绍了6434例髋关节置换术,其中78.5%(4031例)采用MIHA技术植入。唯一具有统计学意义的结果是住院时间缩短(P = 0.02)。两组在手术时间、失血量、脱位和翻修率、神经损伤和围手术期骨折发生率方面没有显著差异,患者选择和外科医生的经验可能对结果有显著影响。例如,报告平均患者年龄为48岁的研究结果与报告平均年龄超过70岁患者的研究结果有显著差异。研究质量得分大多较低,患者数量、随访时间和经过验证的结果测量是最薄弱的环节。
目前,仍然缺乏高质量的证据来支持扩大MIHA的应用。设计更好的研究表明,甚至应进一步将其限制在公认的专家中心。培训和手术技术的改变可能会改变并发症发生率和学习曲线。我们强调在未来比较这两种手术效果的研究中需要精心设计。