Franchini M, Mannucci P M
Transfusion and Hemophilia Center, City Hospital of Verona, Verona, Italy.
J Thromb Haemost. 2007 Nov;5(11):2169-74. doi: 10.1111/j.1538-7836.2007.02750.x.
The effects of air pollution on health have been intensively studied in recent years. Acute exposure to environmental pollutants such as particulate and gaseous matters (carbon monoxide, nitrogen oxides, sulphur dioxide and ozone) was associated with an increased rate of events and mortality because of cardiovascular diseases. These effects were investigated in short-term studies, which related day-to-day variations in air pollution to disease, and in long-term studies, which have followed cohorts of exposed individuals over time. The evidence from the literature on the short-term cardiovascular effects of air pollutants is discussed from clinical and mechanistic points of view.
近年来，空气污染对健康的影响得到了深入研究。急性暴露于环境污染物，如颗粒物和气态物质（一氧化碳、氮氧化物、二氧化硫和臭氧），与心血管疾病导致的事件发生率和死亡率增加有关。这些影响在短期研究中进行了调查，短期研究将空气污染的日常变化与疾病联系起来；在长期研究中也进行了调查，长期研究随时间跟踪暴露个体队列。本文从临床和机制角度讨论了文献中关于空气污染物短期心血管影响的证据。
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