Yuille Martin, van Ommen Gert-Jan, Bréchot Christian, Cambon-Thomsen Anne, Dagher Georges, Landegren Ulf, Litton Jan-Eric, Pasterk Markus, Peltonen Leena, Taussig Mike, Wichmann H-Erich, Zatloukal Kurt
The University of Manchester, School of Translational Medicine, CIGMR Oxford Road, Manchester M13 9PT, UK.
Brief Bioinform. 2008 Jan;9(1):14-24. doi: 10.1093/bib/bbm050. Epub 2007 Oct 23.
Biobanks are well-organized resources comprising biological samples and associated information that are accessible to scientific investigation. Across Europe, millions of samples with related data are held in different types of collections. While individual collections can be well organized and accessible, the resources are subject to fragmentation, insecurity of funding and incompleteness. To address these issues, a Biobanking and BioMolecular Resources Infrastructure (BBMRI) is to be developed across Europe, thereby implementing a European 'roadmap' for research infrastructures that was developed by a forum of EU member states and that has been received by the European Commission. In this review, we describe the work involved in preparing for the construction of BBMRI in a European and global context.
生物样本库是组织有序的资源，包含可供科学研究使用的生物样本及相关信息。在欧洲各地，数百万份带有相关数据的样本存于不同类型的样本库中。虽然各个样本库可能组织有序且便于使用，但这些资源存在分散、资金不稳定和不完整等问题。为解决这些问题，欧洲将建立一个生物样本库和生物分子资源基础设施（BBMRI），从而实施由欧盟成员国论坛制定并已获欧盟委员会认可的欧洲研究基础设施“路线图”。在本综述中，我们描述了在欧洲和全球背景下为建设BBMRI做准备所涉及的工作。
