Nasu Yoshiro, Kurozawa Youichi, Fujiwara Yutaka, Honma Hiroki, Yanai Toshiro, Kido Kenji, Ikeda Takashi
Clinical Research Center for Hand-Arm Vibration Syndrome, Japanese Labor, Health and Welfare Organization, San-in Rosai Hospital, Yonago, Japan.
Int Arch Occup Environ Health. 2008 Apr;81(5):639-44. doi: 10.1007/s00420-007-0273-1. Epub 2007 Oct 25.
A multicenter study (six Rosai hospitals around Japan) was performed to investigate the diagnostic value of changes in finger systolic blood pressure (FSBP) after segmental local cooling for vibration-induced white finger (VWF).
Subjects were 154 men without exposure to vibration and 135 men with occupational vibration exposure. They were classified into four groups: Group A, 154 unexposed control cases; Group B, 21 exposed cases without VWF; Group C, 31 cases with a history of VWF but without any signs of VWF within the last year; and Group D, 83 cases with active VWF within the last year. FSBP% measurements were taken at room temperatures of 23 +/- 1 and 21 +/- 1 degrees C, using a strain-gauge Digimatic 2000 plethysmograph (Medimatic).
At a room temperature of 23 +/- 1 degrees C, there was a significant difference between Groups A and D, and B and D. At a room temperature of 21 +/- 1 degrees C, there was a significant difference between Groups A and C, A and D, and B and D. The values in Group D were the lowest at both room temperatures. Assuming a cut-off value of 75% at 23 +/- 1 degrees C, the sensitivity and specificity were 65.2 and 87.5%, respectively. Assuming the same cut-off value at 21 +/- 1 degrees C, the sensitivity and specificity were 73.9 and 82.5%, respectively. These values were not too high. Most of the subjects with WVF in this study were retired and had not used vibratory tools for many years. The situation of the subjects may affect the results of the FSBP test. Our data did not confirm a difference in diagnostic accuracy between room temperatures of 23 +/- 1 and 21 +/- 1 degrees C.
Our study showed that the sensitivity and specificity of the FSBP test with a cut-off value of 75% at 23 +/- 1 degrees C, were 65.2 and 87.5%, respectively, and at 21 +/- 1 degrees C, they were 73.9 and 82.5%, respectively.
开展一项多中心研究(日本各地的6家罗萨伊医院),以调查分段局部冷却后手指收缩压(FSBP)变化对振动性白指(VWF)的诊断价值。
受试者包括154名未接触振动的男性和135名有职业振动暴露史的男性。他们被分为四组:A组,154例未暴露的对照病例;B组,21例有暴露史但无VWF的病例;C组,31例有VWF病史但在过去一年内无任何VWF体征的病例;D组,83例在过去一年内有活动性VWF的病例。使用应变片式数字2000体积描记仪(Medimatic)在23±1和21±1摄氏度的室温下测量FSBP%。
在23±1摄氏度的室温下,A组与D组、B组与D组之间存在显著差异。在21±1摄氏度的室温下,A组与C组、A组与D组、B组与D组之间存在显著差异。D组在两个室温下的值均最低。假设在23±1摄氏度时的临界值为75%,敏感性和特异性分别为65.2%和87.5%。假设在21±1摄氏度时为相同的临界值,敏感性和特异性分别为73.9%和82.5%。这些值并不太高。本研究中大多数患有WVF的受试者已退休且多年未使用振动工具。受试者的情况可能会影响FSBP测试的结果。我们的数据未证实23±1和21±1摄氏度室温下诊断准确性的差异。
我们的研究表明,在23±1摄氏度时临界值为75%的FSBP测试,敏感性和特异性分别为65.2%和87.5%,在21±1摄氏度时,分别为73.9%和82.5%。