Department of Clinical Physiology, Hvidovre Hospital, University of Copenhagen, Denmark.
Scand J Work Environ Health. 1979 Sep;5(3):249-56. doi: 10.5271/sjweh.3098.
An epidemiologic and clinical study of traumatic vasospastic disease (TVD) was carried out involving 18 workers in a granite quarry. The prevalence of TVD was found to be 72% (95% confidence limits 47-90%) estimated from the combined information from a questionnaire and a clinical interview. The fingers of the hand contralateral to the preferred working hand were the most frequently affected. A newly developed cold provocation test measuring reduction in finger systolic blood pressure during combined body and finger cooling was applied to the quarrymen and to 20 age-matched men in a reference group. Raynaud's phenomenon with digital arterial closure was verified by the measurement of zero pressure in the test finger at 15 or 6 degrees C in 12 of 13 quarrymen with anamnestic and clinical evidence of TVD. The test showed an abnormal response as compared to that of the reference group in all the workers having used vibrating hand tools for more than five years. The precision, estimated as 95% confidence limits from double determinations, was 18.7%. The cold provocation test can be employed diagnostically, and it can also be used to observe the effects of prophylactic measures.
一项针对创伤性血管痉挛病(TVD)的流行病学和临床研究涉及到一家采石场的 18 名工人。通过问卷调查和临床访谈的综合信息,估计该病的患病率为 72%(95%置信区间 47-90%)。从惯用手对侧的手指开始,手的各个手指相继受到影响。我们应用了一种新的冷激发试验,在对采石工人和 20 名年龄匹配的对照组男性进行手指和身体联合降温时,测量手指收缩压的降低情况。在 13 名有 TVD 病史和临床证据的采石工人中,有 12 人通过测量在 15 或 6°C时测试手指的零压力,证实了雷诺现象伴动脉闭塞。与对照组相比,所有使用振动手工具超过五年的工人的试验反应均异常。该测试的精度,根据双测定估计的 95%置信区间为 18.7%。冷激发试验可用于诊断,也可用于观察预防措施的效果。