Saadat Mandana, Nejad Soheila Marzoughian, Habibi Gholamreza, Sheikhvatan Mehrdad
Department of Obstetrics and Gynecology, Bandarabbas University of Medical Sciences, Bandarabbas, Iran.
Taiwan J Obstet Gynecol. 2007 Sep;46(3):255-9. doi: 10.1016/S1028-4559(08)60029-7.
Preeclampsia is a pregnancy-specific hypertensive syndrome associated with significant morbidity and mortality in mother and neonate. We compared neonatal and maternal complications in preeclamptic women with healthy pregnant women.
All 125 consecutive women with preeclampsia at Bandarabbas Shariati Hospital were assessed between July 2005 and July 2006. Parity, type of delivery, common causes of cesarean section, gestational age, birth weight, and neonatal complications and mortality were included as study variables and compared with the control group.
Cesarean section rates were significantly higher in the group with preeclampsia than in the control group (p < 0.05). The mean parity was higher in the normotensive group than in the preeclamptic patients (2.3 +/- 0.65 vs. 3.6 +/- 0.74; p < 0.05). In the preeclamptic women undergoing vaginal delivery, 31% of them underwent induction of labor. The most common indication for induction of labor was severity of preeclampsia (77.8%). Birth weight was statistically significantly lower in women with preeclampsia (p < 0.0001). Among the patients, 5.6% of them were admitted with intrauterine fetal demise, while 111 neonates survived for the remaining patients. The most common causes of neonatal mortality were congenital abnormalities and respiratory distress syndrome.
Gestational age, parity, cesarean section rate, the rate of induced labor, and low birth weight neonates were more frequent in preeclamptic women than in healthy pregnant women.
子痫前期是一种与母亲和新生儿显著发病和死亡相关的妊娠特异性高血压综合征。我们比较了子痫前期妇女与健康孕妇的新生儿和母亲并发症情况。
2005年7月至2006年7月期间,对Bandarabbas Shariati医院连续收治的125例子痫前期妇女进行了评估。将产次、分娩方式、剖宫产常见原因、孕周、出生体重、新生儿并发症及死亡率作为研究变量,并与对照组进行比较。
子痫前期组的剖宫产率显著高于对照组(p < 0.05)。血压正常组的平均产次高于子痫前期患者(2.3 ± 0.65 vs. 3.6 ± 0.74;p < 0.05)。在进行阴道分娩的子痫前期妇女中,31%接受了引产。引产最常见的指征是子痫前期的严重程度(77.8%)。子痫前期妇女的出生体重在统计学上显著较低(p < 0.0001)。在这些患者中,5.6%的患者出现宫内胎儿死亡,其余患者中有111例新生儿存活。新生儿死亡的最常见原因是先天性异常和呼吸窘迫综合征。
子痫前期妇女的孕周、产次、剖宫产率、引产率及低体重儿发生率均高于健康孕妇。