Gunnarsdóttir H, Rafnsson V
Division of Occupational Medicine, Administration of Occupational Safety and Health, Reykjavík, Iceland.
Scand J Soc Med. 1991 Sep;19(3):170-3. doi: 10.1177/140349489101900305.
The purpose of the present study was to describe the cancer pattern in a cohort of farmers in Iceland and to compare their cancer incidence to that of other Icelandic males. This is a retrospective cohort study. The study population was obtained from a register at the Farmers' Pension Fund and comprised 5922 men. Viewed as a whole the cohort shows a significant lower incidence for all tumours than expected. The same is true of SIR for cancer of colon, lung, prostate, bladder and other urinary organs with SIR of 47, 41, 71 and 51, respectively. However, some etiologic factors may contribute to the increased risk of some cancer sites among farmers. There was an excess for Hodgkin's disease SIR 251, and for cancer of lips, skin (excl. melanomas), nervous system, non-Hodgkin's lymphoma and leukemia with SIR of 183, 150, 128, 142 and 151, respectively, however not statistically significant. The authors suggest that something in farmers lifestyle protects them from various kinds of cancer.
本研究的目的是描述冰岛一组农民的癌症模式，并将他们的癌症发病率与其他冰岛男性进行比较。这是一项回顾性队列研究。研究人群来自农民养老基金的登记册，包括5922名男性。总体而言，该队列显示所有肿瘤的发病率显著低于预期。结肠癌、肺癌、前列腺癌、膀胱癌和其他泌尿器官癌症的标准化发病比（SIR）分别为47、41、71和51，情况也是如此。然而，一些病因可能导致农民某些癌症部位的风险增加。霍奇金病的SIR为251，唇癌、皮肤癌（不包括黑色素瘤）、神经系统癌、非霍奇金淋巴瘤和白血病的SIR分别为183、150、128、142和151，存在超额情况，但无统计学意义。作者认为，农民生活方式中的某些因素使他们免受各种癌症的侵害。
