Jain Pankaj, Nijhawan Sandeep, Rai Ramesh Roop, Nepalia Subhash, Mathur Amit
Department of Gastroenterology, SMS Medical College, Jaipur, Rajasthan, India.
World J Gastroenterol. 2007 Nov 21;13(43):5741-4. doi: 10.3748/wjg.v13.i43.5741.
To elucidate the frequency and characteristics of pancreatic involvement in the course of acute (nonfulminant) viral hepatitis.
We prospectively assessed the pancreatic involvement in patients with acute viral hepatitis who presented with severe abdomimanl pain.
We studied 124 patients with acute viral hepatitis, of whom 24 presented with severe abdominal pain. Seven patients (5.65%) were diagnosed to have acute pancreatitis. All were young males. Five patients had pancreatitis in the first week and two in the fourth week after the onset of jaundice. The pancreatitis was mild and all had uneventful recovery from both pancreatitis and hepatitis on conservative treatment. The etiology of pancreatitis was hepatitis E virus in 4, hepatitis A virus in 2, and hepatitis B virus in 1 patient. One patient had biliary sludge along with HEV infection. The abdominal pain of remaining seventeen patients was attributed to stretching of Glisson's capsule.
Acute pancreatitis occurs in 5.65% of patients with acute viral hepatitis, it is mild and recovers with conservative management.
阐明急性（非暴发性）病毒性肝炎病程中胰腺受累的频率及特征。
我们前瞻性评估了出现严重腹痛的急性病毒性肝炎患者的胰腺受累情况。
我们研究了124例急性病毒性肝炎患者，其中24例出现严重腹痛。7例（5.65%）被诊断为急性胰腺炎。所有患者均为年轻男性。5例患者在黄疸出现后的第一周发生胰腺炎，2例在第四周发生。胰腺炎病情较轻，所有患者经保守治疗后胰腺炎和肝炎均顺利康复。胰腺炎的病因在4例患者中为戊型肝炎病毒，2例为甲型肝炎病毒，1例为乙型肝炎病毒。1例患者除戊型肝炎病毒感染外还伴有胆泥。其余17例患者的腹痛归因于肝门管区包膜的牵拉。
急性病毒性肝炎患者中5.65%会发生急性胰腺炎，病情较轻，经保守治疗可康复。
