Karaus Alexander, Merboldt Klaus-Dietmar, Graessner Joachim, Frahm Jens
Biomedizinische NMR Forschungs GmbH am Max-Planck-Institut für biophysikalische Chemie, Göttingen, Germany.
J Magn Reson Imaging. 2007 Dec;26(6):1666-71. doi: 10.1002/jmri.21208.
To develop a rapid stimulated echo acquisition mode (STEAM) MRI technique for "black-blood" imaging of the human heart that overcomes the single-slice limitation and partially compromised blood suppression associated with double inversion-recovery techniques.
Black-blood multislice images of the heart along anatomic orientations and triggered to end diastole were obtained from healthy human subjects at 3T using rapid STEAM MRI sequences with five-eighths partial Fourier encoding and variable flip angles. Single-shot STEAM images at 2.5 x 2.5 mm2 in-plane resolution and 6-mm section thickness were recorded in 230 msec from individual heartbeats. Improved signal-to-noise ratio (SNR) and higher spatial resolution of 2.0 x 2.0 mm2 and 1.5 x 1.5 mm2 were achieved by segmented multishot STEAM MRI with interleaved k-space acquisitions (160 msec each) from several heartbeats. In a single breathhold covering 18 heartbeats selected applications employed either three segments with six sections or six segments with three sections.
Because stimulated echoes (STEs) dephase signals from moving spins, rapid STEAM images are free from blood signal contamination. The method offers a flexible tradeoff between spatial resolution, imaging speed (i.e., number of segments), and volume coverage (i.e., number of sections).
Rapid STEAM MRI of the heart emerges as a simple technique for multislice imaging of the myocardial wall with efficient flow suppression.
开发一种快速刺激回波采集模式(STEAM)磁共振成像(MRI)技术,用于人体心脏的“黑血”成像,该技术可克服单层面限制以及与双反转恢复技术相关的部分血液抑制效果不佳的问题。
使用具有八分之五部分傅里叶编码和可变翻转角的快速STEAM MRI序列,在3T条件下从健康人体受试者获取沿解剖方向且触发至舒张末期的心脏黑血多层图像。以2.5×2.5 mm2的平面分辨率和6 mm的层厚,在230毫秒内记录来自各个心跳的单次激发STEAM图像。通过分段多次激发STEAM MRI,从多个心跳中进行交错的k空间采集(每次160毫秒),实现了2.0×2.0 mm2和1.5×1.5 mm2的更高空间分辨率以及改进的信噪比(SNR)。在一次覆盖18个心跳的屏气过程中,选定的应用采用了三段六层面或六段三层面的方式。
由于刺激回波(STE)会使来自移动自旋的信号去相位,因此快速STEAM图像不存在血液信号污染。该方法在空间分辨率、成像速度(即段数)和容积覆盖范围(即层数)之间提供了灵活的权衡。
心脏快速STEAM MRI成为一种用于心肌壁多层成像且具有有效血流抑制的简单技术。