Mani Venkatesh, Itskovich Vitalii V, Aguiar Silvia H, Mizsei Gabor, Aguinaldo Juan Gilberto S, Samber Daniel D, Macaluso Frank M, Fayad Zahi A
Imaging Science Laboratories, Mount Sinai School of Medicine, New York, New York 10029-6574, USA.
J Magn Reson Imaging. 2005 Nov;22(5):628-33. doi: 10.1002/jmri.20428.
To comparatively analyze two fast in vivo multislice black-blood carotid artery vessel wall imaging techniques with and without cardiac gating.
Eight subjects with carotid artery atherosclerosis, and four healthy subjects were studied using two black-blood multislice techniques: rapid extended coverage double inversion recovery (REX-DIR), and inflow/outflow saturation band (IOSB) rapid acquisition with relaxation enhancement (RARE) multislice acquisitions. Quantitative, qualitative, and morphometric analyses were performed on images.
Gating produced significantly lower values for the REX-DIR sequence with respect to signal intensity in muscle and the carotid artery wall, whereas it had no effect on flow suppression compared to non-gated images. For the IOSB sequences, gating had no significant effect on signal intensity of muscle and the carotid artery wall, but worsened flow suppression. REX-DIR and IOSB sequences were statistically different with respect to signal intensity of muscle (with REX-DIR sequences having lower values), while no statistical significance was observed for flow suppression and wall delineation. A morphologic analysis of the vessel wall and lumen comparing REX-DIR gated, IOSB gated, REX-DIR non-gated, and IOSB non-gated sequences revealed no significant differences between the acquisition techniques tested.
Non-gated sequences may be used instead of gated sequences in atherosclerotic vessel wall imaging without compromising image quality. This may shorten examination time and improve patient comfort.
比较分析两种快速的体内多层黑血颈动脉血管壁成像技术，一种采用心脏门控，另一种不采用心脏门控。
对8名患有颈动脉粥样硬化的受试者和4名健康受试者使用两种黑血多层技术进行研究：快速扩展覆盖双反转恢复（REX-DIR），以及流入/流出饱和带（IOSB）快速采集弛豫增强（RARE）多层采集。对图像进行定量、定性和形态学分析。
对于REX-DIR序列，门控使肌肉和颈动脉壁的信号强度值显著降低，而与非门控图像相比，其对血流抑制无影响。对于IOSB序列，门控对肌肉和颈动脉壁的信号强度无显著影响，但会加重血流抑制。REX-DIR和IOSB序列在肌肉信号强度方面存在统计学差异（REX-DIR序列的值较低），而在血流抑制和壁勾勒方面未观察到统计学意义。对血管壁和管腔进行形态学分析，比较REX-DIR门控、IOSB门控、REX-DIR非门控和IOSB非门控序列，结果显示所测试的采集技术之间无显著差异。
在动脉粥样硬化血管壁成像中，非门控序列可替代门控序列使用，而不影响图像质量。这可能会缩短检查时间并提高患者舒适度。
