老年人的多重用药与围手术期用药

Polypharmacy and perioperative medications in the elderly.

作者信息

Barnett Sheila Ryan

机构信息

Harvard Medical School, Department of Anesthesiology, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.

出版信息

Anesthesiol Clin. 2009 Sep;27(3):377-89, table of contents. doi: 10.1016/j.anclin.2009.07.004.

DOI:10.1016/j.anclin.2009.07.004

PMID:19825482

Abstract

Polypharmacy is a significant and complex problem affecting more than 40% of the geriatric population. Accurate medication histories may be difficult to obtain, but must include over-the-counter remedies as well as prescription. Physiologic changes occur with aging that predispose elderly patients to adverse drug events. At a minimum, medications with significant anticholinergic properties should be recognized and avoided in the perioperative period.

摘要

多重用药是一个重大且复杂的问题，影响着超过40%的老年人群。准确的用药史可能难以获取，但必须包括非处方药以及处方药。随着年龄增长会出现生理变化，这使老年患者易发生药物不良事件。至少，在围手术期应识别并避免使用具有显著抗胆碱能特性的药物。