溴隐亭对阿扑吗啡反应性勃起功能障碍患者的疗效：一项开放性研究。
Effect of bromocriptine in patients with apomorphine-responsive erectile impotence: an open study.
作者信息
Lal S, Kiely M E, Thavundayil J X, Stewart J D, Assalian P, Ackman C F
机构信息
Department of Psychiatry, Montreal General Hospital, Quebec, Canada.
出版信息
J Psychiatry Neurosci. 1991 Dec;16(5):262-6.
Abstract
An open pilot study was undertaken to investigate the therapeutic effect of the dopaminergic agent, bromocriptine (BC), in impotent patients who developed an erectile response to the dopamine receptor agonist, apomorphine. Eight out of 17 patients reported improvement in ability to obtain an erection; five of these 8 subjects were able to achieve penetration. The optimum dose of BC was 2.5 - 11.25 mg/day. A double-blind placebo-controlled study is merited.
摘要
开展了一项开放性试验研究，以调查多巴胺能药物溴隐亭（BC）对那些对多巴胺受体激动剂阿扑吗啡产生勃起反应的阳痿患者的治疗效果。17名患者中有8名报告勃起能力有所改善；这8名受试者中有5名能够完成性交插入。BC的最佳剂量为2.5 - 11.25毫克/天。值得进行一项双盲安慰剂对照研究。
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本文引用的文献
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Effect of sulpiride, an atypical neuroleptic, on apomorphine-induced growth hormone secretion.非典型抗精神病药物舒必利对阿扑吗啡诱导的生长激素分泌的影响。
Brain Res Bull. 1982 Jun;8(6):587-91. doi: 10.1016/0361-9230(82)90085-5.
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Pharmacotherpay of sexual impotence in the male.男性性功能障碍的药物治疗。
Mod Probl Pharmacopsychiatry. 1980;15:158-73. doi: 10.1159/000402342.
3
Cavernosal alpha-blockade: a new technique for investigating and treating erectile impotence.海绵体α-阻滞剂：一种用于研究和治疗勃起功能障碍的新技术。
Br J Psychiatry. 1983 Oct;143:332-7. doi: 10.1192/bjp.143.4.332.
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Effect of apomorphine, a dopamine receptor agonist, on penile tumescence in normal subjects.多巴胺受体激动剂阿扑吗啡对正常受试者阴茎勃起的影响。
Prog Neuropsychopharmacol Biol Psychiatry. 1984;8(4-6):695-9. doi: 10.1016/0278-5846(84)90040-x.
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The yawning-penile erection syndrome as a model for putative dopamine autoreceptor activity.打呵欠-阴茎勃起综合征作为假定多巴胺自身受体活性的模型。
Eur J Pharmacol. 1984 Aug 3;103(1-2):81-9. doi: 10.1016/0014-2999(84)90192-4.
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