Kecelj-Leskovec Nada, Jezersek Matija, Mozina Janez, Pavlović Milos D, Lunder Tomaz
Department of Dermatovenereology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Wound Repair Regen. 2007 Sep-Oct;15(5):767-71. doi: 10.1111/j.1524-475X.2007.00300.x.
A lack of reproducible and practical methods to assess venous leg ulcer healing is a major problem encountered by investigators evaluating various treatments. We aimed to compare a new laser-based three-dimensional (3D) measuring device with computer planimetry with photography for the assessment of venous leg ulcers, and to estimate the reliability of measurements by the methods. Sixty measurements of perimeter and area of 15 venous leg ulcers, < 10 cm in diameter (eight patients; six females; mean age 71 years; range 52-90 years), were made with both methods. Two independent investigators performed the measurements at the first visit and 2-4 weeks later. The precision and accuracy of the methods were determined and compared. The accuracies for computer planimetry with photography in comparison with the laser-based 3D measuring method were 8.4% for perimeter and 16.0% for area measurements. The precisions of ulcer area and perimeter measurements did not differ significantly between the two methods (p=0.993 and 0.201, respectively). The main advantage of the laser-based measuring method is the 3D ulcer measurement with a precision of 7.5%, which also takes into account distortions created by the limb convexity. The system is accurate, inexpensive, user-friendly, and appropriate for everyday practice.
缺乏可重复且实用的方法来评估下肢静脉溃疡的愈合情况，这是评估各种治疗方法的研究人员所面临的一个主要问题。我们旨在比较一种基于激光的新型三维（3D）测量设备与计算机平面测量法及摄影法在评估下肢静脉溃疡方面的效果，并评估这些方法测量结果的可靠性。使用这两种方法对15个直径小于10厘米的下肢静脉溃疡（8例患者；6名女性；平均年龄71岁；范围52 - 90岁）进行了60次周长和面积测量。两名独立研究人员在首次就诊时及2 - 4周后进行测量。确定并比较了这些方法的精密度和准确性。与基于激光的3D测量方法相比，计算机平面测量法及摄影法在周长测量方面的准确性为8.4%，在面积测量方面为16.0%。两种方法在溃疡面积和周长测量的精密度上无显著差异（分别为p = 0.993和0.201）。基于激光的测量方法的主要优点是能够进行3D溃疡测量，精密度为7.5%，还考虑到了肢体凸度造成的变形。该系统准确、廉价、用户友好，适用于日常临床实践。
