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硬膜内面神经鞘瘤:诊断与治疗问题

Intradural facial nerve schwannoma: diagnostic and therapeutic problems.

作者信息

Kohmura Eiji, Aihara Hideo, Miyake Shigeru, Fujita Atsushi

机构信息

Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Japan.

出版信息

Skull Base. 2007 May;17(3):215-22. doi: 10.1055/s-2007-977463.

Abstract

OBJECTIVES

To define characteristics of intradural facial schwannoma (FS) and discuss management strategies.

METHOD

Retrospective review of clinical charts.

RESULTS

Six patients were diagnosed, based on surgical findings, as having intradural FS. None of the patients complained initially of facial weakness, but all showed severe disturbance of hearing function assessed on admission. FS was suspected in four of our six patients because of imaging findings or facial palsy caused by a small tumor. Total removal was performed in five cases followed by facial nerve reconstruction, and nearly total removal was performed in one case. Most patients recovered to Grade II or III palsy during the follow-up, and long-lasting palsy before surgery showed poor recovery.

CONCLUSION

Imaging findings such as tumor extension to the middle fossa and clinical findings such as facial palsy caused by a small tumor strongly suggest a diagnosis of FS. Facial function can be restored satisfactorily for most patients after appropriate surgery.

摘要

目的

明确硬膜内面神经鞘瘤(FS)的特征并探讨治疗策略。

方法

对临床病历进行回顾性分析。

结果

根据手术结果,6例患者被诊断为硬膜内FS。所有患者最初均无面部无力主诉,但入院时听力功能均严重受损。6例患者中有4例因影像学表现或小肿瘤导致的面瘫而怀疑为FS。5例行肿瘤全切并同期行面神经重建,1例行次全切除。多数患者随访期间恢复至Ⅱ或Ⅲ级面瘫,术前长期面瘫者恢复较差。

结论

肿瘤向中颅窝扩展等影像学表现及小肿瘤导致的面瘫等临床表现强烈提示FS诊断。多数患者经适当手术治疗后面部功能可得到满意恢复。

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本文引用的文献

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Facial nerve schwannomas: different manifestations and outcomes.面神经鞘瘤:不同表现及预后
Surg Neurol. 2004 Sep;62(3):245-52; discussion 452. doi: 10.1016/j.surneu.2003.09.034.
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Facial nerve schwannoma: surgical excision versus conservative management.面神经鞘瘤:手术切除与保守治疗
Ann Otol Rhinol Laryngol. 2001 Nov;110(11):1025-9. doi: 10.1177/000348940111001106.
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Facial nerve grading system.面神经分级系统。
Otolaryngol Head Neck Surg. 1985 Apr;93(2):146-7. doi: 10.1177/019459988509300202.
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Intracranial and intratemporal facial neuroma.颅内及颞骨内面神经瘤。
Otolaryngol Head Neck Surg. 1987 Jan;96(1):71-9. doi: 10.1177/019459988709600113.

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