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手术治疗内听道及桥小脑角面神经鞘瘤。

Surgical management of internal auditory canal and cerebellopontine angle facial nerve schwannoma.

机构信息

Department of Otolaryngology, University of Iowa, Iowa 52249, USA.

出版信息

Otol Neurotol. 2012 Aug;33(6):1071-6. doi: 10.1097/MAO.0b013e31825e7e36.

Abstract

OBJECTIVE

To investigate the long-term patient outcomes after tumor debulking for internal auditory canal facial schwannoma (FNS).

STUDY DESIGN

Retrospective case review.

SETTING

Tertiary referral center.

PATIENTS

Patients operated on between 1998 and 2010 for a preoperative diagnosis of vestibular schwannoma with the intraoperative identification FNS instead.

INTERVENTION

Diagnostic and therapeutic.

MAIN OUTCOME MEASURES

House-Brackmann facial nerve score immediately and at long-term follow-up (>1 yr); recurrence of tumor.

RESULTS

Sixteen patients were identified who were presumed to have vestibular schwannoma but intraoperatively were diagnosed with facial nerve schwannoma. Eleven underwent debulking surgery (67%-99% tumor removal), 2 underwent decompression only, 2 were diagnosed with nervus intermedius tumors and had total tumor removal with preservation of the motor branch of cranial nerve VII, and 1 had complete tumor removal with facial nerve grafting. Five of 11 debulking patients underwent the middle cranial fossa approach for tumor removal; the remainder had translabyrinthine resections. One debulking patient was lost to follow-up. Nine of 10 patients with long-term follow-up had House-Brackmann Grade I or II facial function. One patient had recurrence of the tumor that required revision surgery with total removal and facial nerve grafting.

CONCLUSION

Tumor debulking for FNS provides an opportunity for tumor removal and excellent facial nerve function. Continuous facial nerve monitoring is vital for successful debulking surgery. FNS debulking is feasible via the middle cranial fossa approach. Serial postoperative imaging is warranted to monitor for recurrence.

摘要

目的

研究内听道面神经鞘瘤(FNS)肿瘤减容术后的长期患者结局。

研究设计

回顾性病例研究。

设置

三级转诊中心。

患者

1998 年至 2010 年间因术前诊断为前庭神经鞘瘤而接受手术,术中发现为面神经鞘瘤的患者。

干预

诊断和治疗。

主要观察指标

House-Brackmann 面神经评分即刻和长期随访(>1 年);肿瘤复发。

结果

共确定 16 例患者,术前诊断为前庭神经鞘瘤,但术中诊断为面神经鞘瘤。11 例行肿瘤部分切除术(67%-99%肿瘤切除),2 例行减压术,2 例诊断为中间神经肿瘤,行面神经保留颅神经 VII 运动支的全切除,1 例行面神经移植的全切除。11 例肿瘤部分切除术患者中有 5 例行中颅窝入路切除肿瘤;其余患者行迷路切除术。1 例肿瘤部分切除术患者失访。10 例长期随访患者中有 9 例 House-Brackmann 分级为 I 或 II 级面神经功能。1 例患者肿瘤复发,需行再次手术切除并面神经移植。

结论

FNS 的肿瘤减容术为肿瘤切除和良好的面神经功能提供了机会。持续的面神经监测对于成功的肿瘤减容术至关重要。通过中颅窝入路可行 FNS 肿瘤减容术。需行连续术后影像学检查以监测肿瘤复发。

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Evolution in the management of facial nerve schwannoma.面神经鞘瘤治疗的演变。
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