Romeo Javier, González-Gross Marcela, Wärnberg Julia, Díaz Ligia E, Marcos Ascensión
Grupo Inmunonutrición, Departamento de Metabolismo y Nutrición, Instituto del Frío, Consejo Superior de Investigaciones Científicas, C/José Antonio Novais, 10, 28040 Madrid, Spain.
Nutr Metab Cardiovasc Dis. 2008 Jun;18(5):365-72. doi: 10.1016/j.numecd.2007.03.007. Epub 2007 Oct 31.
To analyse the association of moderate beer consumption on the blood lipid profile in healthy Spanish adults.
The study had an intervention longitudinal design in which each subject established their own control with a previous wash-out phase. After a 30-day alcohol abstinence period, 57 healthy volunteers were submitted to a daily moderate intake of beer for 30 days. Serum total cholesterol, HDL-cholesterol, triacylglycerols, GOT, GPT, GGT and glucose values, as well as blood erythrocytes, haemoglobin, haematocrit and MCV levels, together with anthropometric parameters were determined at the beginning of the study (baseline levels) (a), after 1 month of alcoholic abstinence (b) and after 1 month of moderate beer consumption (c). Dietary intake was assessed twice by a 7-day dietary record. HDL-cholesterol, erythrocytes, haematocrit and MCV levels increased significantly (p<0.05) after moderate beer consumption in women. In men, a decrease in HDL-cholesterol levels was observed after alcohol abstention. Haematocrit and MCV counts also increased significantly (p<0.05) in men after moderate beer consumption. There were no dietary changes during the study.
In healthy Spanish adults, the effects of moderate beer consumption during 1 month were associated with favourable changes on the blood lipid profile.
分析适量饮用啤酒与西班牙健康成年人血脂谱之间的关联。
本研究采用干预性纵向设计,每位受试者在经过一个洗脱期后建立自身对照。在30天戒酒期后,57名健康志愿者连续30天每日适量饮用啤酒。在研究开始时(基线水平)(a)、戒酒1个月后(b)以及适量饮用啤酒1个月后(c),测定血清总胆固醇、高密度脂蛋白胆固醇、三酰甘油、谷草转氨酶、谷丙转氨酶、γ-谷氨酰转肽酶和葡萄糖值,以及血液红细胞、血红蛋白、血细胞比容和平均红细胞体积水平,同时测定人体测量参数。通过7天饮食记录对饮食摄入进行了两次评估。适量饮用啤酒后,女性的高密度脂蛋白胆固醇、红细胞、血细胞比容和平均红细胞体积水平显著升高(p<0.05)。在男性中,戒酒期间观察到高密度脂蛋白胆固醇水平下降。适量饮用啤酒后,男性的血细胞比容和平均红细胞体积计数也显著增加(p<0.05)。研究期间饮食无变化。
在西班牙健康成年人中,1个月内适量饮用啤酒的影响与血脂谱的有利变化有关。