Mena P, Maynar M, Gutierrez J M, Maynar J, Timon J, Campillo J E
Department of Physiology, Faculty of Medicine, University of Extremadura, Badajoz, Spain.
Int J Sports Med. 1991 Dec;12(6):563-6. doi: 10.1055/s-2007-1024734.
This study was designed to investigate the influence of endurance training on the activities of the scavenger enzymes superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) measured in erythrocytes from sedentary subjects, amateur bicycle racers and in professional bicycle racers who were cycling in two real cyclist contests including the top-class race Vuelta a España (VCE). Under resting conditions the SOD activity was higher (p less than 0.01) in cyclists than in controls. The activities of CAT and GSH-Px were higher (p less than 0.05 and p less than 0.01, respectively) under resting conditions in professional cyclists versus measured both in sedentary subjects and amateur cyclists. The enzyme activities were not modified significantly in professional cyclists after a bout of exercise of 22 km in 5 hrs, but the SOD activity was increased (p less than 0.05) and CAT activity reduced (p less than 0.05) after 2800 km in 20 days (VCE). The present results shown that aerobic endurance training, when at a professional level, produces an increase in the erythrocyte activities of the main free radicals scavenger enzymes.
本研究旨在调查耐力训练对超氧化物歧化酶（SOD）、过氧化氢酶（CAT）和谷胱甘肽过氧化物酶（GSH-Px）活性的影响，这些酶的活性是在久坐不动的受试者、业余自行车赛车手以及参加了包括顶级赛事环西班牙自行车赛（VCE）在内的两项真实自行车比赛的职业自行车赛车手的红细胞中测量的。在静息状态下，自行车赛车手的SOD活性高于对照组（p<0.01）。与久坐不动的受试者和业余自行车赛车手相比，职业自行车赛车手在静息状态下的CAT和GSH-Px活性更高（分别为p<0.05和p<0.01）。职业自行车赛车手在5小时内骑行22公里的运动后，酶活性没有显著改变，但在20天内骑行2800公里（VCE）后，SOD活性增加（p<0.05），CAT活性降低（p<0.05）。目前的结果表明，当达到专业水平时，有氧耐力训练会使主要自由基清除酶的红细胞活性增加。
