School of Sport Sciences, University of Extremadura, Avenida de la Universidad s/n, 10003, Cáceres, Spain.
Movement, Brain and Health Research Group (MOBhE), Center of Higher Education Alberta Gim´enez (Comillas Pontifical University), Palma de Mallorca, Balearic Islands, Spain.
J Int Soc Sports Nutr. 2021 Apr 7;18(1):28. doi: 10.1186/s12970-021-00426-4.
Physical training produces changes in the extracellular and intracellular concentrations of trace minerals elements. To our knowledge, only three compartments have been studied simultaneously. The aim of the present study was to analyze the influence of physical training on extracellular (serum, plasma and urine) and intracellular (erythrocytes and platelets) concentrations of Copper (Cu).
Forty young men participated in this study. The participants were divided into a training group (TG; n = 20; 18.15 ± 0.27 years; 68.59 ± 4.18 kg; 1.76 ± 0.04 m) and a control group (CG; n = 20; 19.25 ± 0.39 years; 73.45 ± 9.04 kg; 1.79 ± 0.06 m). The TG was formed by semi-professional soccer players from a youth category with a regular training plan of 10 h/week. All of them had been participating in high level competitions and had trained for at least 5 years. Plasma, serum, urine, erythrocyte and platelet samples of Cu were obtained and analyzed by inductively coupled plasma mass spectrometry (ICP-MS).
The TG showed lower concentrations of Cu in erythrocytes (p < 0.05) despite similar intakes. There were no significant differences in Cu concentrations in plasma, serum, urine and platelets although the trend was similar to that observed in erythrocytes.
The assessment of trace element concentrations should be carried out in both extracellular and intracellular compartments to obtain a proper evaluation and to identify possible deficiencies of the element. We believe that additional Cu supplementation is needed in athletes who perform physical training regularly.
体育锻炼会引起痕量矿物质元素在细胞外液和细胞内液中的浓度变化。据我们所知，目前仅有三个隔室同时被研究过。本研究旨在分析体育锻炼对铜（Cu）的细胞外液（血清、血浆和尿液）和细胞内液（红细胞和血小板）浓度的影响。
本研究共纳入 40 名年轻男性。将参与者分为训练组（TG；n=20；18.15±0.27 岁；68.59±4.18kg；1.76±0.04m）和对照组（CG；n=20；19.25±0.39 岁；73.45±9.04kg；1.79±0.06m）。TG 由半职业足球运动员组成，他们来自一个青年队，有规律的每周 10 小时的训练计划。他们都参加过高水平的比赛，并且已经训练了至少 5 年。通过电感耦合等离子体质谱法（ICP-MS）检测并分析了 Cu 在血浆、血清、尿液、红细胞和血小板中的浓度。
尽管摄入相似，但 TG 中的 Cu 浓度在红细胞中较低（p<0.05）。血浆、血清、尿液和血小板中的 Cu 浓度没有显著差异，尽管其趋势与红细胞中观察到的相似。
应同时评估细胞外液和细胞内液中的痕量元素浓度，以进行适当的评估并确定元素可能缺乏。我们认为，经常进行体育锻炼的运动员需要额外补充 Cu。
