Arai Satoko, Shinohara Yuka, Kato Yasuyuki, Hirano Satoshi, Yoshizawa Atsuto, Hojyo Masaaki, Kobayashi Nobuyuki, Sugiyama Haruhito, Kudo Koichiro
Department of Respiratory Medicine, International Medical Center of Japan, Japan.
Arerugi. 2007 Oct;56(10):1293-7.
A 51-year-old man was admitted to our hospital with fever, dry cough and dyspnea. He had taken minocycline for 11 days because of urinary tract infection. Chest X-ray on admission showed diffuse reticular shadows in bilateral lung fields with bilateral pleural effusion. Cessation of minocycline led to spontaneous improvement of symptoms and radiographic findings. The lymphocyte stimulation test for minocycline with peripheral blood and pleural effusion were negative. After provocation test with minocycline, he developed fever and dry cough and bilateral ground glass opacity appeared on his chest X-ray. He was diagnosed as minocycline-induced pneumonitis and recovered rapidly following corticosteroid therapy.
一名51岁男性因发热、干咳和呼吸困难入院。他因尿路感染服用米诺环素11天。入院时胸部X线显示双侧肺野弥漫性网状阴影伴双侧胸腔积液。停用米诺环素后症状和影像学表现自发改善。米诺环素外周血和胸腔积液淋巴细胞刺激试验均为阴性。米诺环素激发试验后，他出现发热、干咳，胸部X线显示双侧磨玻璃影。他被诊断为米诺环素诱发的肺炎，糖皮质激素治疗后迅速康复。
