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从治疗到实验模型:向人类受试者施用内毒素的百年历程。

From therapy to experimental model: a hundred years of endotoxin administration to human subjects.

作者信息

Bahador Marjan, Cross Alan S

机构信息

Center for Vaccine Development and Division of Infectious Diseases, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

出版信息

J Endotoxin Res. 2007;13(5):251-79. doi: 10.1177/0968051907085986.

DOI:10.1177/0968051907085986
PMID:17986486
Abstract

This article is a review of studies in which endotoxin has been administered to human subjects for experimental purposes. Data are presented in tabular form so the reader can better appreciate the objectives of individual studies. Although the original intention was to focus on the adverse events associated with these studies, unexpected serious adverse events rarely have been reported.

摘要

本文是一篇对为实验目的而将内毒素施用于人类受试者的研究的综述。数据以表格形式呈现,以便读者能更好地理解各项研究的目的。尽管最初的意图是关注与这些研究相关的不良事件,但很少有意外严重不良事件的报告。

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