Franco Ramon A
Division of Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston 02114, USA.
Curr Opin Otolaryngol Head Neck Surg. 2007 Dec;15(6):387-93. doi: 10.1097/MOO.0b013e3282f19ef2.
To describe the current support in the literature for in-office surgery using the 585-nm pulsed dye laser.
There are substantial cost savings (US$5000) and patient comfort when in-office surgery is performed with the pulsed dye laser. The pulsed dye laser can be used in the office and operating room to activate aminolevulinic acid for photodynamic treatment of recalcitrant laryngeal keratosis, with long-term eradication of keratosis without the prolonged photosensitivity of previous photodynamic agents. The site of the cleavage plane created in the true vocal fold mucosa has now been elucidated.
The 585-nm pulsed dye laser allows safe, medically effective and cost-effective in-office surgery for a host of laryngeal lesions such as papillomatosis, keratosis, Reinke's edema, granulomas and other vascular lesions. The pulsed dye laser can activate aminolevulinic acid for laryngeal photodynamic therapy. Of the lasers currently in use it has the longest track record of safety and, to the satisfaction of many, continues in service at 23 centers around the world.
描述目前文献中对使用585纳米脉冲染料激光进行门诊手术的支持情况。
使用脉冲染料激光进行门诊手术可大幅节省成本（5000美元）并提高患者舒适度。脉冲染料激光可在门诊和手术室中用于激活氨基乙酰丙酸，以光动力治疗顽固性喉角化病，可长期消除角化病，且不会出现以往光动力剂导致的长时间光敏反应。目前已阐明在真声带黏膜中形成的分裂平面位置。
585纳米脉冲染料激光可为一系列喉部病变，如乳头状瘤病、角化病、任克氏水肿、肉芽肿及其他血管性病变，提供安全、医学上有效且具成本效益的门诊手术。脉冲染料激光可激活氨基乙酰丙酸用于喉部光动力治疗。在目前使用的激光中，它具有最长的安全使用记录，令许多人满意的是，它仍在全球23个中心使用。
