Videnovic Aleksandar, Metman Leo Verhagen
Section of Movement Disorders, Rush University Medical Center, Chicago, Illinois 60612, USA.
Mov Disord. 2008 Feb 15;23(3):343-9. doi: 10.1002/mds.21753.
Deep brain stimulation (DBS) has assumed a prominent role in the treatment of Parkinson's disease (PD). In this manuscript, we attempt to estimate the prevalence and categorize adverse events (AEs) of DBS in PD, based on efficacy studies published over the last decade. We conclude that reliable categorization and quantification of AEs based on available data poses many challenges and argue that a standardized scheme for reporting AEs should be created. This would provide a foundation for a meaningful risk/benefit analysis, for comparison of results between centers and, ultimately, for a well informed decision by physicians and patients as to whether surgery should be pursued.
深部脑刺激（DBS）在帕金森病（PD）治疗中已占据重要地位。在本手稿中，我们试图根据过去十年发表的疗效研究，估算PD患者中DBS不良事件（AE）的发生率并对其进行分类。我们得出结论，基于现有数据对AE进行可靠的分类和量化面临诸多挑战，并认为应创建一个标准化的AE报告方案。这将为有意义的风险/效益分析、中心间结果比较提供基础，并最终为医生和患者就是否应进行手术做出明智决策提供依据。
