子宫肌瘤女性甲状腺结节和乳腺纤维瘤的发病率增加。
Increased frequency of thyroid nodules and breast fibroadenomas in women with uterine fibroids.
作者信息
Spinos Nikitas, Terzis George, Crysanthopoulou Athina, Adonakis George, Markou Kostas B, Vervita Vasiliki, Koukouras Dimitrios, Tsapanos Vasilios, Decavalas George, Kourounis George, Georgopoulos Neoklis A
机构信息
Department of Obstetrics and Gynecology, University of Patras Medical School, Rio, Patras, Greece.
出版信息
Thyroid. 2007 Dec;17(12):1257-9. doi: 10.1089/thy.2006.0330.
Fibroids or leiomyomas or myomas of the uterus are the most common benign gynecologic disease, while fibroadenomas of the breast are most frequently seen in young women, usually within 20 years after puberty. Multiple tumors in one or both breasts are found in 10-15% of patients. Single thyroid nodules are much more common in women than in men, and their prevalence increases with age. The aim of the present study was to determine cross-sectionally the incidence of solitary thyroid nodules and fibroadenomas of the breast in women with uterine fibroids. In women with uterine adenomas, the frequency of fibroadenomas of the breast was 65% and of thyroid nodules was 38.7%, while in women with a normal uterus, the frequency was 35% and 20%, respectively. Therefore, women with uterine fibroids have an increased incidence of thyroid nodules (t = 4.68, p = 0.030) and of fibroadenomas of the breast (t = 11.74, p = 0.001).
子宫肌瘤或子宫平滑肌瘤是最常见的妇科良性疾病，而乳腺纤维腺瘤在年轻女性中最为常见，通常在青春期后的20年内出现。10%至15%的患者在一侧或双侧乳房中发现多个肿瘤。单个甲状腺结节在女性中比在男性中更为常见，并且其患病率随年龄增长而增加。本研究的目的是横断面确定患有子宫肌瘤的女性中孤立性甲状腺结节和乳腺纤维腺瘤的发生率。在患有子宫腺瘤的女性中，乳腺纤维腺瘤的发生率为65%，甲状腺结节的发生率为38.7%，而在子宫正常的女性中，发生率分别为35%和20%。因此，患有子宫肌瘤的女性甲状腺结节（t = 4.68，p = 0.030）和乳腺纤维腺瘤（t = 11.74，p = 0.001）的发生率增加。
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